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    KAS III 3-ketoacyl-acyl carrier protein synthase III [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842561, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KAS III
    Official Full Name
    3-ketoacyl-acyl carrier protein synthase III
    Primary source
    TAIR:AT1G62640
    Locus tag
    AT1G62640
    See related
    Araport:AT1G62640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-ketoacyl-acyl carrier protein synthase III; 3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III; T3P18.20; T3P18_20
    Summary
    3-ketoacyl-acyl carrier protein synthase III (KAS III)
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    Genomic context

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    See KAS III in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (23192146..23195103)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene Flavin-binding monooxygenase family protein Neighboring gene Disease resistance protein (CC-NBS-LRR class) family Neighboring gene miscRNA Neighboring gene Glycosyl hydrolases family 32 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. De novo biosynthesis of fatty acids plays critical roles in the response of the photosynthetic machinery to low temperature in Arabidopsis. Takami T, et al. Plant Cell Physiol, 2010 Aug. PMID 20547590
    2. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. kas3 mutants are defective in thylakoid protein accumulation at low temperature.
      Title: De novo biosynthesis of fatty acids plays critical roles in the response of the photosynthetic machinery to low temperature in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_001036144.2
    NM_104942.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables beta-ketoacyl-acyl-carrier-protein synthase III activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    3-ketoacyl-acyl carrier protein synthase III
    NP_001031221.1
    • 3-ketoacyl-acyl carrier protein synthase III (KAS III); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, 3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity; INVOLVED IN: lipid biosynthetic process, metabolic process, fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (InterPro:IPR013751), Beta-ketoacyl-acyl carrier protein synthase III (FabH) (InterPro:IPR004655); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_176452.1
    • 3-ketoacyl-acyl carrier protein synthase III (KAS III); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, 3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity; INVOLVED IN: lipid biosynthetic process, metabolic process, fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (InterPro:IPR013751), Beta-ketoacyl-acyl carrier protein synthase III (FabH) (InterPro:IPR004655); Has 11800 Blast hits to 11794 proteins in 2811 species: Archae - 187; Bacteria - 7763; Metazoa - 5; Fungi - 2; Plants - 1625; Viruses - 0; Other Eukaryotes - 2218 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23192146..23195103
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104942.4 → NP_176452.1  3-ketoacyl-acyl carrier protein synthase III [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176452.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49243, P93722, Q9SI84, Q9SXD3
      UniProtKB/TrEMBL
      A0A5S9WS16, A0A654EW34, B9DHF9
      Conserved Domains (2) summary
      PLN02326
      Location:23 → 403
      PLN02326; 3-oxoacyl-[acyl-carrier-protein] synthase III
      cd00830
      Location:69 → 401
      KAS_III; Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl ...

    2. NM_001036144.2 → NP_001031221.1  3-ketoacyl-acyl carrier protein synthase III [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031221.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49243, P93722, Q9SI84, Q9SXD3
      UniProtKB/TrEMBL
      A0A5S9WS16, A0A654EW34, B9DHF9
      Conserved Domains (2) summary
      PLN02326
      Location:23 → 403
      PLN02326; 3-oxoacyl-[acyl-carrier-protein] synthase III
      cd00830
      Location:69 → 401
      KAS_III; Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P49243.2

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