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    Galactose oxidase/kelch repeat superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844383, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Galactose oxidase/kelch repeat superfamily protein
    Primary source
    TAIR:AT1G80440
    Locus tag
    AT1G80440
    See related
    Araport:AT1G80440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Kelch repeat F-box 20; KFB20; KISS ME DEADLY 1; KMD1; T21F11.23; T21F11_23
    Summary
    Encodes a member of a family of F-box proteins, called the KISS ME DEADLY (KMD) family, that targets type-B ARR proteins for degradation and is involved in the negative regulation of the cytokinin response. Also named as KFB20, a member of a group of Kelch repeat F-box proteins that negatively regulate phenylpropanoid biosynthesis by targeting the phenypropanoid biosynthesis enzyme phenylalanine ammonia-lyase.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (30241452..30243176)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene BRCT domain-containing DNA repair protein Neighboring gene tRNA-Ser Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene VQ motif-containing protein Neighboring gene Actin-like ATPase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and validation of the wound and insect bite early inducible promoter from Arabidopsis thaliana. Mishra DK, et al. 3 Biotech, 2022 Mar. PMID 35251877, Free PMC Article
    2. Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase. Zhang X, et al. Plant Cell, 2013 Dec. PMID 24363316, Free PMC Article
    3. SCF(KMD) controls cytokinin signaling by regulating the degradation of type-B response regulators. Kim HJ, et al. Proc Natl Acad Sci U S A, 2013 Jun 11. PMID 23720308, Free PMC Article
    4. Down-regulation of Kelch domain-containing F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to ultraviolet radiation. Zhang X, et al. Plant Physiol, 2015 Feb. PMID 25502410, Free PMC Article
    5. ABC transporter PEN3/PDR8/ABCG36 interacts with calmodulin that, like PEN3, is required for Arabidopsis nonhost resistance. Campe R, et al. New Phytol, 2016 Jan. PMID 26315018

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_106692.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of cytokinin-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of phenylpropanoid metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Galactose oxidase/kelch repeat superfamily protein
    NP_565238.1
    • Galactose oxidase/kelch repeat superfamily protein; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Kelch related (InterPro:IPR013089), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT1G15670.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30241452..30243176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106692.4 → NP_565238.1  Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565238.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBH0, Q9M8L2
      UniProtKB/TrEMBL
      A0A654EQT9, A0A7G2E4F3
      Conserved Domains (3) summary
      PHA03098
      Location:80 → 245
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:106 → 149
      Kelch; KELCH repeat [structural motif]
      pfam00646
      Location:4 → 47
      F-box; F-box domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8L2.1

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