Protein phosphatase 2C family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Protein phosphatase 2C family protein
Primary source: TAIR:AT3G16800
Locus tag: AT3G16800
See related: Araport:AT3G16800
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (5720941..5723185)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The EGR (clade E growth-regulating (EGR) type 2C protein phosphatases)-MASP1 (microtubule-associated stress protein 1 (MASP1; AT4G03260) system selectively regulates microtubule recovery and stability to adjust plant growth and cell expansion in response to changing environmental conditions.
Title: Protein Phosphatase 2Cs and Microtubule-Associated Stress Protein 1 Control Microtubule Stability, Plant Growth, and Drought Response.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001338260.1

Supported by ESTs:

NM_001338262.1

Supported by ESTs:

NM_001338263.1

Supported by ESTs:

NM_112554.3

Supported by ESTs:

NM_180268.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within drought recovery	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within negative regulation of growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein dephosphorylation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in nucleus	HDA more info	PubMed
colocalizes_with plasma membrane	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: Protein phosphatase 2C family protein

NP_001319572.1

Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT5G27930.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_188303.1

Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT5G27930.2); Has 6043 Blast hits to 6037 proteins in 299 species: Archae - 0; Bacteria - 10; Metazoa - 1467; Fungi - 737; Plants - 2641; Viruses - 5; Other Eukaryotes - 1183 (source: NCBI BLink).

NP_850599.2

Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C, N-terminal (InterPro:IPR014045), Protein phosphatase 2C (InterPro:IPR015655); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT5G27930.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

5720941..5723185

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001338261.1 → NP_001326939.1 Protein phosphatase 2C family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LQT0

Conserved Domains (1) summary

cd00143
Location:1 → 253

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_112554.3 → NP_188303.1 Protein phosphatase 2C family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188303.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LPG8, Q9LRZ4

UniProtKB/TrEMBL

A0A178VME2, A0A5S9XD03, A0A7G2ELF8, F4J3W4

Conserved Domains (1) summary

cd00143
Location:61 → 348

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_001338262.1 → NP_001326938.1 Protein phosphatase 2C family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LQS9
NM_001338263.1 → NP_001326940.1 Protein phosphatase 2C family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LQT0

Conserved Domains (1) summary

cd00143
Location:1 → 253

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_180268.4 → NP_850599.2 Protein phosphatase 2C family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_850599.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LPG8, Q9LRZ4

UniProtKB/TrEMBL

A0A178VME2, A0A5S9XD03, A0A7G2ELF8, F4J3W4

Conserved Domains (1) summary

cd00143
Location:61 → 348

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_001338260.1 → NP_001319572.1 Protein phosphatase 2C family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LPG8, Q9LRZ4

UniProtKB/TrEMBL

A0A178VME2, A0A5S9XD03, A0A7G2ELF8, F4J3W4

Conserved Domains (1) summary

cd00143
Location:61 → 348

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...