AFP2 ABI five binding protein 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: AFP2
Official Full Name: ABI five binding protein 2
Primary source: TAIR:AT1G13740
Locus tag: AT1G13740
See related: Araport:AT1G13740
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ABI five binding protein 2; F21F23.17; F21F23_17
Summary: Encodes a member of a small plant-specific gene family whose members interact with ABI5 and appear to be involved in mediating stress responses. AFP2 mutants affect a number of ABA mediated processes such as germination and response to osmotic and sugar stress. AFP2 nuclear localization is stress dependent.
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Genomic context

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See AFP2 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 2

Sequence:: Chromosome: 1; NC_003070.9 (4713433..4715407)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SOS2-AFP2 module regulates seed germination by inducing ABI5 degradation in response to salt stress in Arabidopsis.
Title: SOS2-AFP2 module regulates seed germination by inducing ABI5 degradation in response to salt stress in Arabidopsis.
AFP2 recruits the corepressor TPR2 to coordinate the CO protein signal and thereby ensure that flowering occurs at an appropriate time.
Title: ABI5-BINDING PROTEIN2 Coordinates CONSTANS to Delay Flowering by Recruiting the Transcriptional Corepressor TPR2.
SOM is reported to negatively regulate seeds germination by altering GA/ABA metabolism, here we found that AFP2 and ABI5 altered SOM transcription. Data demonstrate that AFP2 is a novel regulator to control high temperature-induced secondary seed dormancy through ABI5 and SOM.
Title: AFP2 as the novel regulator breaks high-temperature-induced seeds secondary dormancy through ABI5 and SOM in Arabidopsis thaliana.
Results suggest that the ABI5/ABF binding proteins (AFPs) AFP1 and AFP2 participate in multiple mechanisms modulating abscisic Acid (ABA) response.
Title: ABI5-binding proteins (AFPs) alter transcription of ABA-induced genes via a variety of interactions with chromatin modifiers.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_101242.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: ABI five binding protein 2

NP_563933.1

ABI five binding protein 2 (AFP2); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1675 (InterPro:IPR012463); BEST Arabidopsis thaliana protein match is: ABI five binding protein (TAIR:AT1G69260.1); Has 207 Blast hits to 201 proteins in 26 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 6; Plants - 185; Viruses - 3; Other Eukaryotes - 8 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

4713433..4715407

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101242.3 → NP_563933.1 ABI five binding protein 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_563933.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93ZQ8, Q9LMX5

UniProtKB/TrEMBL

A0A178WBB1, A0A5S9U9Q2

Conserved Domains (3) summary

pfam07897
Location:54 → 88

EAR; Ethylene-responsive binding factor-associated repression

pfam16135
Location:309 → 339

Jas; TPL-binding domain in jasmonate signalling

pfam16136
Location:107 → 181

NINJA_B; Putative nuclear localization signal