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    CDEF1 GDSL-like Lipase/Acylhydrolase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829137, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDEF1
    Official Full Name
    GDSL-like Lipase/Acylhydrolase superfamily protein
    Primary source
    TAIR:AT4G30140
    Locus tag
    AT4G30140
    See related
    Araport:AT4G30140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CUTICLE DESTRUCTING FACTOR 1; CUTICLE DESTRUCTING FACTOR 1; F6G3.170; F6G3_170
    Summary
    Member of the GDSL lipase/esterase family of proteins that functions as cutinase. Expressed in pollen and at the zone of lateral root emergence.
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    Genomic context

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    See CDEF1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14738326..14740742, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene heavy metal atpase 2 Neighboring gene heavy metal atpase 3 Neighboring gene DUF630 family protein (DUF630 and DUF632) Neighboring gene Urb2/Npa2 family protein Neighboring gene villin 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ectopic expression of an esterase, which is a candidate for the unidentified plant cutinase, causes cuticular defects in Arabidopsis thaliana. Takahashi K, et al. Plant Cell Physiol, 2010 Jan. PMID 19996150
    2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CDEF1 (cuticle destructing factor 1), is a candidate gene encoding a cutinase that belongs to the GDSL lipase/esterase family. [CDEF1]
      Title: Ectopic expression of an esterase, which is a candidate for the unidentified plant cutinase, causes cuticular defects in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_119160.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cutinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDSL-like Lipase/Acylhydrolase superfamily protein
    NP_194743.1
    • CUTICLE DESTRUCTING FACTOR 1 (CDEF1); FUNCTIONS IN: cutinase activity, carboxylesterase activity; INVOLVED IN: lipid metabolic process; LOCATED IN: extracellular space; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: GDSL-like Lipase/Acylhydrolase superfamily protein (TAIR:AT2G19050.1); Has 3175 Blast hits to 3140 proteins in 124 species: Archae - 0; Bacteria - 141; Metazoa - 0; Fungi - 4; Plants - 3022; Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14738326..14740742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119160.3 → NP_194743.1  GDSL-like Lipase/Acylhydrolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194743.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LD78, Q9SZW7
      UniProtKB/TrEMBL
      A0A178V2L8, A0A5S9XXJ7, A0A654FU57
      Conserved Domains (1) summary
      cd01837
      Location:32 → 336
      SGNH_plant_lipase_like; a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SZW7.1

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