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    TOPP5 type one serine/threonine protein phosphatase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823835, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOPP5
    Official Full Name
    type one serine/threonine protein phosphatase 5
    Primary source
    TAIR:AT3G46820
    Locus tag
    AT3G46820
    See related
    Araport:AT3G46820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    type one serine/threonine protein phosphatase 5
    Summary
    Encodes the catalytic subunit of a Type 1 phosphoprotein Ser/Thr phosphatase, expressed in roots, shoots and flowers.
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    Genomic context

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    See TOPP5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (17241702..17244281, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene RAB GTPase homolog A2C Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of Protein Phosphatase1 Regulatory Subunit3 in Mediating the Abscisic Acid Response. Zhang J, et al. Plant Physiol, 2020 Nov. PMID 32948668, Free PMC Article
    2. Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana. Smith RD, et al. Plant Mol Biol, 1993 Jan. PMID 7678768
    3. Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit. Templeton GW, et al. Biochem J, 2011 Apr 1. PMID 21222654
    4. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
    5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_114549.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to abscisic acid stimulus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    part_of protein phosphatase type 1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type one serine/threonine protein phosphatase 5
    NP_190266.1
    • type one serine/threonine protein phosphatase 5 (TOPP5); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 2 (TAIR:AT5G59160.3); Has 7127 Blast hits to 6926 proteins in 615 species: Archae - 78; Bacteria - 490; Metazoa - 2413; Fungi - 1415; Plants - 987; Viruses - 13; Other Eukaryotes - 1731 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17241702..17244281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114549.4 → NP_190266.1  type one serine/threonine protein phosphatase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190266.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48485, Q29Q41, Q570F3
      UniProtKB/TrEMBL
      A0A178VFV2, A0A5S9XIK6, A0A7G2ET45
      Conserved Domains (1) summary
      cd07414
      Location:13 → 304
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48485.1

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