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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832332, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT5G22690
    Locus tag
    AT5G22690
    See related
    Araport:AT5G22690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MDJ22.11; MDJ22_11
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (7541072..7545256)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box/RNI-like/FBD-like domains-containing protein Neighboring gene F-box protein Neighboring gene LOW protein: F-box/FBD/LRR-like protein Neighboring gene F-box/FBD/LRR protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001343748.1
    NM_001343749.1
    NM_122175.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_197661.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G46470.1); Has 15956 Blast hits to 11549 proteins in 387 species: Archae - 12; Bacteria - 480; Metazoa - 758; Fungi - 10; Plants - 14383; Viruses - 0; Other Eukaryotes - 313 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7541072..7545256
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343747.1 → NP_001331342.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDK2, A0A5S9Y6C2

    2. NM_122175.3 → NP_197661.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197661.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULZ4, Q9FNJ2
      Conserved Domains (5) summary
      PLN03210
      Location:4 → 992
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:636 → 658
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:10 → 175
      TIR; TIR domain
      pfam07725
      Location:612 → 631
      LRR_3; Leucine Rich Repeat
      cl17190
      Location:210 → 240
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    3. NM_001343748.1 → NP_001331341.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULZ4, A0A1P8BDP8

    4. NM_001343749.1 → NP_001331343.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULZ4, A0A1P8BDK0
    Nucleotide Protein
    Heading Accession and Version

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