AAP6 amino acid permease 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: AAP6
Official Full Name: amino acid permease 6
Primary source: TAIR:AT5G49630
Locus tag: AT5G49630
See related: Araport:AT5G49630
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: amino acid permease 6; MNI5.1; MNI5_1
Summary: Is a high affinity amino acid transporter capable of transporting aspartate and tryptophan. May be involved in the amino acid uptake from xylem.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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CRISPR/Cas9-induced knockout of an amino acid permease gene (AAP6) reduced Arabidopsis thaliana susceptibility to Meloidogyne incognita.
Title: CRISPR/Cas9-induced knockout of an amino acid permease gene (AAP6) reduced Arabidopsis thaliana susceptibility to Meloidogyne incognita.
The transport of amino acids by AAP3 and AAP6 is important for nematode infection and success of the progeny.
Title: The amino acid permeases AAP3 and AAP6 are involved in root-knot nematode parasitism of Arabidopsis.
The total amino acid concentration of SE sap of the aap6 mutant plants was significantly lower than that of the wild-type plants.
Title: A mutation in amino acid permease AAP6 reduces the amino acid content of the Arabidopsis sieve elements but leaves aphid herbivores unaffected.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_124341.4

Function	Evidence Code	Pubs
enables acidic amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino acid transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables neutral L-amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within aspartate transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within tryptophan transport	IDA Inferred from Direct Assay more info	PubMed

NP_199774.1

amino acid permease 6 (AAP6); FUNCTIONS IN: acidic amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, amino acid transmembrane transporter activity; INVOLVED IN: response to water deprivation, response to salt stress, aspartate transport, tryptophan transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: amino acid permease 1 (TAIR:AT1G58360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain