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    NRPB6A RNA polymerase Rpb6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835269, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPB6A
    Official Full Name
    RNA polymerase Rpb6
    Primary source
    TAIR:AT5G51940
    Locus tag
    AT5G51940
    See related
    Araport:AT5G51940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MSG15.2; MSG15_2; NRPD6A; NRPE6A
    Summary
    One of two highly similar proteins that can serve as a non-catalytic subunit of nuclear DNA-dependent RNA polymerases II, IV and V; homologous to budding yeast RPB6 and the E. coli RNA polymerase omega subunit. Probably redundant with At2g04630.
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    Genomic context

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    See NRPB6A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (21104551..21105947)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Pyridoxal phosphate (PLP)-dependent transferases superfamily protein Neighboring gene Glucose-methanol-choline (GMC) oxidoreductase family protein Neighboring gene Glucose-methanol-choline (GMC) oxidoreductase family protein Neighboring gene complex 1 protein, LYR family protein Neighboring gene GroES-like zinc-binding alcohol dehydrogenase family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Zhong X, et al. Proc Natl Acad Sci U S A, 2015 Jan 20. PMID 25561521, Free PMC Article
    2. SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV. Law JA, et al. PLoS Genet, 2011 Jul. PMID 21811420, Free PMC Article
    3. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124573.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase IV complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase V complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase Rpb6
    NP_200007.1
    • NRPB6A; FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding; INVOLVED IN: transcription, DNA-dependent; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, core complex, DNA-directed RNA polymerase IV complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, 14-18kDa subunit, conserved site (InterPro:IPR020708), RNA polymerase subunit, RPB6/omega (InterPro:IPR012293), RNA polymerase Rpb6 (InterPro:IPR006110), DNA-directed RNA polymerase, 14-18kDa subunit (InterPro:IPR006111); BEST Arabidopsis thaliana protein match is: RNA polymerase Rpb6 (TAIR:AT2G04630.1); Has 907 Blast hits to 906 proteins in 313 species: Archae - 223; Bacteria - 0; Metazoa - 99; Fungi - 194; Plants - 79; Viruses - 16; Other Eukaryotes - 296 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21104551..21105947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124573.3 → NP_200007.1  RNA polymerase Rpb6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200007.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FJ98
      UniProtKB/TrEMBL
      A0A178UA32, A0A178VSG9, A0A5S9YD59
      Conserved Domains (1) summary
      PLN00152
      Location:5 → 135
      PLN00152; DNA-directed RNA polymerase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJ98.1

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