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    PLR1 NAD(P)-linked oxidoreductase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835440, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLR1
    Official Full Name
    NAD(P)-linked oxidoreductase superfamily protein
    Primary source
    TAIR:AT5G53580
    Locus tag
    AT5G53580
    See related
    Araport:AT5G53580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPLR1; MNC6.12; MNC6_12; pyridoxal reductase 1
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    Genomic context

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    See PLR1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (21764937..21767013, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene YELLOW STRIPE like 3 Neighboring gene cytochrome B5 isoform E Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene FBD-like domain family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis. Herrero S, et al. Plant Mol Biol, 2011 May. PMID 21533842
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that At5g53580 is a homologue of the S. pombe PLR1 (pyridoxal reductase) and encodes a protein with PL reductase activity.
      Title: Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_124738.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NADPH binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxine:NADP 4-dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pyridoxal 5'-phosphate salvage IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pyridoxal biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in vitamin B6 catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    NAD(P)-linked oxidoreductase superfamily protein
    NP_200170.2
    • NAD(P)-linked oxidoreductase superfamily protein; FUNCTIONS IN: oxidoreductase activity, aldo-keto reductase activity; INVOLVED IN: oxidation reduction; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldo/keto reductase (InterPro:IPR001395), Aldo/keto reductase subgroup (InterPro:IPR020471), Aldo/keto reductase, conserved site (InterPro:IPR018170); BEST Arabidopsis thaliana protein match is: NAD(P)-linked oxidoreductase superfamily protein (TAIR:AT1G06690.1); Has 29267 Blast hits to 29250 proteins in 2546 species: Archae - 568; Bacteria - 19101; Metazoa - 2030; Fungi - 2126; Plants - 1340; Viruses - 0; Other Eukaryotes - 4102 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21764937..21767013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124738.4 → NP_200170.2  NAD(P)-linked oxidoreductase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200170.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56Y42, Q6NKP1, Q9FJC6
      UniProtKB/TrEMBL
      A0A178UCB0, A0A5S9YDY0
      Conserved Domains (2) summary
      cd06660
      Location:45 → 347
      Aldo_ket_red; Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial ...
      COG0667
      Location:39 → 354
      Tas; Predicted oxidoreductase (related to aryl-alcohol dehydrogenase) [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56Y42.1

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