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    CYP81F2 cytochrome P450, family 81, subfamily F, polypeptide 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835828, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP81F2
    Official Full Name
    cytochrome P450, family 81, subfamily F, polypeptide 2
    Primary source
    TAIR:AT5G57220
    Locus tag
    AT5G57220
    See related
    Araport:AT5G57220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; family 81; MJB24.3; MJB24_3; polypeptide 2; polypeptide 2''; subfamily F
    Summary
    member of CYP81F, involved in glucosinolate metabolism. Mutants had impaired resistance to fungi.
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    Genomic context

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    See CYP81F2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (23187840..23189902)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene phosphatidylserine decarboxylase 2 Neighboring gene ENTH/ANTH/VHS superfamily protein Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene Thioredoxin superfamily protein Neighboring gene OSBP(oxysterol binding protein)-related protein 4C Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The gene controlling the indole glucosinolate modifier1 quantitative trait locus alters indole glucosinolate structures and aphid resistance in Arabidopsis. Pfalz M, et al. Plant Cell, 2009 Mar. PMID 19293369, Free PMC Article
    2. De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew. Hunziker P, et al. Plant Cell Environ, 2020 Jun. PMID 32275065
    3. A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense. Bednarek P, et al. Science, 2009 Jan 2. PMID 19095900
    4. Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101. van de Mortel JE, et al. Plant Physiol, 2012 Dec. PMID 23073694, Free PMC Article
    5. Glucosinolate metabolites required for an Arabidopsis innate immune response. Clay NK, et al. Science, 2009 Jan 2. PMID 19095898, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. study identifed CYP81F2 as the gene underlying Indole Glucosinolate Modifier1 (IGM1), a metabolic QTL for accumulation of 2 modified indole glucosinolates; also CYP81F2 contributes to defense against green peach aphid
      Title: The gene controlling the indole glucosinolate modifier1 quantitative trait locus alters indole glucosinolate structures and aphid resistance in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_125104.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response by callose deposition in cell wall IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to insect IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within indole glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within indole glucosinolate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within induced systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450, family 81, subfamily F, polypeptide 2
    NP_200532.1
    • ''cytochrome P450, family 81, subfamily F, polypeptide 2'' (CYP81F2); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: in 7 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 81, subfamily F, polypeptide 3 (TAIR:AT4G37400.1); Has 35927 Blast hits to 35660 proteins in 1834 species: Archae - 77; Bacteria - 5490; Metazoa - 12066; Fungi - 7231; Plants - 9556; Viruses - 3; Other Eukaryotes - 1504 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23187840..23189902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125104.3 → NP_200532.1  cytochrome P450, family 81, subfamily F, polypeptide 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200532.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LVD6
      UniProtKB/TrEMBL
      A0A178UNW5, A0A5S9YF16, C3W7I0
      Conserved Domains (1) summary
      cd20653
      Location:62 → 476
      CYP81; cytochrome P450 family 81
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LVD6.1

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