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    Neurochondrin neurochondrin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40796, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Neurochondrinprovided by FlyBase
    Official Full Name
    neurochondrinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037447
    Locus tag
    Dmel_CG2330
    See related
    AllianceGenome:FB:FBgn0037447
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2330; Dmel\CG2330; NCDN
    Summary
    Involved in muscle system process. Predicted to be located in neuronal cell body. Predicted to be active in dendrite. Is expressed in several structures, including adult head; larval muscle cell; larval muscle system; somatic muscle primordium; and visceral mesoderm derivative. Orthologous to human NCDN (neurochondrin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Neurochondrin in Genome Data Viewer
    Location:
    83E8-83E8; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6468437..6471016)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2294159..2296738)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mir-9375 stem loop Neighboring gene Zinc-finger protein Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Methionine-CAT 1-5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of the evolutionarily conserved muscle myofibrillar matrix by cell type dependent and independent mechanisms. Ajayi PT, et al. Nat Commun, 2022 May 13. PMID 35562354, Free PMC Article
    2. Circadian rhythm-dependent alterations of gene expression in Drosophila brain lacking fragile X mental retardation protein. Xu S, et al. PLoS One, 2012. PMID 22655085, Free PMC Article
    3. The effect of a synergistic concentration of a Piper nigrum extract used in conjunction with pyrethrum upon gene expression in Drosophila melanogaster. Jensen HR, et al. Insect Mol Biol, 2006 Jun. PMID 16756552
    4. Metallophosphoesterase regulates light-induced rhodopsin endocytosis by promoting an association between arrestin and the adaptor protein AP2. Mu Y, et al. J Biol Chem, 2019 Aug 30. PMID 31324721, Free PMC Article
    5. Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network. Jakobsen JS, et al. Genes Dev, 2007 Oct 1. PMID 17908931, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in muscle system process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in muscle system process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of neuronal synaptic plasticity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in neuronal cell body ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    neurochondrin
    Names
    CG2330-PA
    Neurochondrin-PA
    dNeurochondrin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6468437..6471016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141401.2 → NP_649658.1  neurochondrin [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649658.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MSV0, Q9VI25
      UniProtKB/TrEMBL
      B3DNM6
      Related
      FBpp0081226
      Conserved Domains (1) summary
      pfam05536
      Location:2 → 631
      Neurochondrin; Neurochondrin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI25.1 Q9VI25

    Gene LinkOut

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