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    CG10947 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35309, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10947provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032857
    Locus tag
    Dmel_CG10947
    See related
    AllianceGenome:FB:FBgn0032857
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38C.42; Dmel\CG10947
    Summary
    Predicted to enable calmodulin-lysine N-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be located in cytoplasm and nucleus. Is expressed in antennal disc; eye disc; leg disc; and wing disc. Orthologous to human CAMKMT (calmodulin-lysine N-methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10947 in Genome Data Viewer
    Location:
    38C6-38C6; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20385293..20414800, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20385293..20414800, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 37 member A1 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 2/3 complex, subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic basis and repeatability for desiccation resistance in Drosophila melanogaster (Diptera: Drosophilidae). Fanara JJ, et al. Genetica, 2024 Feb. PMID 38102503
    2. New components of Drosophila leg development identified through genome wide association studies. Grubbs N, et al. PLoS One, 2013. PMID 23560084, Free PMC Article
    3. Map position and expression of the genes in the 38 region of Drosophila. Butler H, et al. Genetics, 2001 Aug. PMID 11514449, Free PMC Article
    4. Notch and Ras signaling pathway effector genes expressed in fusion competent and founder cells during Drosophila myogenesis. Artero R, et al. Development, 2003 Dec. PMID 14602676
    5. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c20414190-20414151 mobile_element_type = transposon:INE-1{}4780

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables calmodulin-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10947-PB
    CG10947-PC
    CG10947-PD
    NP_610031.1
    NP_724261.1
    NP_724262.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20385293..20414800 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136187.3 → NP_610031.1  uncharacterized protein Dmel_CG10947, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610031.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V0X6, Q32KE9
      Related
      FBpp0307726
      Conserved Domains (1) summary
      cl17173
      Location:199 → 352
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. NM_165328.3 → NP_724261.1  uncharacterized protein Dmel_CG10947, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724261.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V0X6, Q32KE9
      Related
      FBpp0080901
      Conserved Domains (1) summary
      cl17173
      Location:199 → 352
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    3. NM_165329.3 → NP_724262.1  uncharacterized protein Dmel_CG10947, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724262.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V0X6, Q32KE9
      Related
      FBpp0080902
      Conserved Domains (1) summary
      cl17173
      Location:199 → 352
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4V0X6 A4V0X6
    Q95TY4 Q95TY4

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