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    Dpy-30L1 Dpy-30-like 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34480, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dpy-30L1provided by FlyBase
    Official Full Name
    Dpy-30-like 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0032293
    Locus tag
    Dmel_CG6444
    See related
    AllianceGenome:FB:FBgn0032293
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6444; dDPY30-L1; Dmel\CG6444; dpy-30L1; dpy30; Dpy30; DPY30
    Summary
    Part of MLL3/4 complex and Set1C/COMPASS complex. Is expressed in brain; gonad; imaginal disc; and salivary gland. Orthologous to human DPY30 (dpy-30 histone methyltransferase complex regulatory subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dpy-30L1 in Genome Data Viewer
    Location:
    32A5-32A5; 2-43 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10732653..10733307)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10732653..10733307)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ER membrane protein complex subunit 3 Neighboring gene Nucleoporin 107kD Neighboring gene Vacuolar H[+] ATPase 16kD subunit 5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. Vardanyan A, et al. BMC Dev Biol, 2008 Jun 27. PMID 18588663, Free PMC Article
    2. Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Herz HM, et al. Genes Dev, 2012 Dec 1. PMID 23166019, Free PMC Article
    3. Fragile X protein functions with lgl and the par complex in flies and mice. Zarnescu DC, et al. Dev Cell, 2005 Jan. PMID 15621528
    4. The COMPASS family of H3K4 methylases in Drosophila. Mohan M, et al. Mol Cell Biol, 2011 Nov. PMID 21875999, Free PMC Article
    5. COMPASS and SWI/SNF complexes in development and disease. Cenik BK, et al. Nat Rev Genet, 2021 Jan. PMID 32958894

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of MLL1/2 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of MLL3/4 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Set1C/COMPASS complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Set1C/COMPASS complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Dpy-30-like 1
    Names
    CG6444-PA
    Dpy-30L1-PA
    Dumpy-30-like 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10732653..10733307
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135601.4 → NP_609445.1  Dpy-30-like 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609445.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DMX8, Q9VKQ9
      Related
      FBpp0079701
      Conserved Domains (1) summary
      pfam05186
      Location:77 → 118
      Dpy-30; Dpy-30 motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKQ9.1 Q9VKQ9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
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