Cdc16 Cell division cycle 16 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cdc16provided by FlyBase
Official Full Name: Cell division cycle 16provided by FlyBase
Primary source: FLYBASE:FBgn0025781
Locus tag: Dmel_CG6759
See related: AllianceGenome:FB:FBgn0025781
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Apc6; APC6; cdc16; CDC16; CG6759; Dmcdc16; Dmel\CG6759
Summary: Involved in several processes, including compound eye photoreceptor cell differentiation; negative regulation of canonical Wnt signaling pathway; and positive regulation of mitotic metaphase/anaphase transition. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytoplasm. Is expressed in adult head; wing hinge primordium; and wing pouch. Orthologous to human CDC16 (cell division cycle 16). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (23281201..23284123)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (19106923..19109845)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Apc6/Cdc16 and Apc8/Cdc23 silencing induces developmental delay and causes different pupal lethality
Title: Structurally related TPR subunits contribute differently to the function of the anaphase-promoting complex in Drosophila melanogaster.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in anaphase-promoting complex-dependent catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell division	IBA Inferred from Biological aspect of Ancestor more info
involved_in compound eye photoreceptor cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in compound eye photoreceptor cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic cell cycle	HMP more info	PubMed
involved_in negative regulation of canonical Wnt signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of mitotic metaphase/anaphase transition	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitotic metaphase/anaphase transition	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic metaphase/anaphase transition	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of anaphase-promoting complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain