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    COX10 cytochrome c oxidase 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819059, updated on 18-Sep-2024

    Summary

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    Official Symbol
    COX10
    Official Full Name
    cytochrome c oxidase 10
    Primary source
    TAIR:AT2G44520
    Locus tag
    AT2G44520
    See related
    Araport:AT2G44520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cytochrome c oxidase 10; F4I1.50; F4I1_50
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    Genomic context

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    See COX10 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (18379527..18381959)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene CDK inhibitor P21 binding protein Neighboring gene NADH dehydrogenase ubiquinone 1 alpha subcomplex assembly factor-like protein (DUF498/DUF598) Neighboring gene Phosphoribosyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtCOX10, a protein involved in haem o synthesis during cytochrome c oxidase biogenesis, is essential for plant embryogenesis and modulates the progression of senescence. Mansilla N, et al. J Exp Bot, 2015 Nov. PMID 26246612
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtCOX10 was localized in mitochondria and was able to restore growth of a yeast Deltacox10 null mutant on non-fermentable carbon sources. Plants with T-DNA insertions in the coding region of both copies of AtCOX10 could not be recovered.
      Title: AtCOX10, a protein involved in haem o synthesis during cytochrome c oxidase biogenesis, is essential for plant embryogenesis and modulates the progression of senescence.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_130015.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protoheme IX farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome c oxidase 10
    NP_566019.1
    • cytochrome c oxidase 10 (COX10); FUNCTIONS IN: protoheme IX farnesyltransferase activity, prenyltransferase activity; INVOLVED IN: heme o biosynthetic process, heme biosynthetic process; LOCATED IN: integral to membrane, mitochondrial membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protohaem IX farnesyltransferase, mitochondria (InterPro:IPR016315), Protohaem IX farnesyltransferase (InterPro:IPR006369), UbiA prenyltransferase (InterPro:IPR000537); Has 7990 Blast hits to 7990 proteins in 1845 species: Archae - 160; Bacteria - 4430; Metazoa - 177; Fungi - 179; Plants - 66; Viruses - 0; Other Eukaryotes - 2978 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18379527..18381959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130015.4 → NP_566019.1  cytochrome c oxidase 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566019.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64886, Q94AL4
      UniProtKB/TrEMBL
      A0A178VUK2, A0A5S9X709
      Conserved Domains (1) summary
      PLN02776
      Location:101 → 431
      PLN02776; prenyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64886.4

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