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    FT1 fucosyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814851, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FT1
    Official Full Name
    fucosyltransferase 1
    Primary source
    TAIR:AT2G03220
    Locus tag
    AT2G03220
    See related
    Araport:AT2G03220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    2)-FUCOSYLTRANSFERASE; A-(1; ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE 1; ATFT1; ATFUT1; fucosyltransferase 1; FUT1; MUR2; MURUS 2; T18E12.11; T18E12_11; XYLOGLUCAN FUCOSYLTRANSFERASE
    Summary
    member of Glycosyltransferase Family- 37
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    Genomic context

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    See FT1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (970245..972416, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene fucosyltransferase 2 Neighboring gene EXS (ERD1/XPR1/SYG1) family protein Neighboring gene GCK domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana α1,2-l-fucosyltransferase catalyzes the transfer of l-galactose to xyloglucan oligosaccharides. Ohashi H, et al. FEBS Lett, 2019 Jan. PMID 30478825
    2. Expression, purification and biochemical characterization of AtFUT1, a xyloglucan-specific fucosyltransferase from Arabidopsis thaliana. Cicéron F, et al. Biochimie, 2016 Sep-Oct. PMID 27580247
    3. The galactoside 2-α-L-fucosyltransferase FUT1 from Arabidopsis thaliana: crystallization and experimental MAD phasing. Rocha J, et al. Acta Crystallogr F Struct Biol Commun, 2016 Jul. PMID 27380374, Free PMC Article
    4. Xyloglucan fucosyltransferase, an enzyme involved in plant cell wall biosynthesis. Perrin RM, et al. Science, 1999 Jun 18. PMID 10373113
    5. Protein-protein interactions among xyloglucan-synthesizing enzymes and formation of Golgi-localized multiprotein complexes. Chou YH, et al. Plant Cell Physiol, 2015 Feb. PMID 25392066

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study demonstrate that FUT1 exhibits L-galactosyltransferase activity toward xyloglucan oligosaccharides when GDP-L-Gal is used as a substrate instead of GDP-L-Fuc.
      Title: Arabidopsis thaliana α1,2-l-fucosyltransferase catalyzes the transfer of l-galactose to xyloglucan oligosaccharides.
    2. Recombinant FUT1 from Arabidopsis thaliana was crystallized in two different crystal forms.
      Title: The galactoside 2-α-L-fucosyltransferase FUT1 from Arabidopsis thaliana: crystallization and experimental MAD phasing.
    3. Data indicate that fucosyltransferase 1 (AtFUT1) behaves as a non-covalent homodimer in solution.
      Title: Expression, purification and biochemical characterization of AtFUT1, a xyloglucan-specific fucosyltransferase from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_126373.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fucosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables fucosyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables galactoside 2-alpha-L-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell wall biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within plant-type cell wall biogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within xyloglucan biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in Golgi medial cisterna HDA PubMed 

    General protein information

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    Preferred Names
    fucosyltransferase 1
    NP_178421.1
    • fucosyltransferase 1 (FT1); FUNCTIONS IN: transferase activity, transferring glycosyl groups, fucosyltransferase activity; INVOLVED IN: plant-type cell wall biogenesis, xyloglucan biosynthetic process; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Xyloglucan fucosyltransferase (InterPro:IPR004938); BEST Arabidopsis thaliana protein match is: fucosyltransferase 7 (TAIR:AT1G14070.1); Has 329 Blast hits to 320 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 326; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      970245..972416 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126373.3 → NP_178421.1  fucosyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178421.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81052, Q9SWH5
      UniProtKB/TrEMBL
      A0A654F2D1, W8PV36
      Conserved Domains (1) summary
      cl16914
      Location:83 → 531
      O-FucT_like; GDP-fucose protein O-fucosyltransferase and related proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SWH5.2

    Gene LinkOut

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