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    PIP proline iminopeptidase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815913, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP
    Official Full Name
    proline iminopeptidase
    Primary source
    TAIR:AT2G14260
    Locus tag
    AT2G14260
    See related
    Araport:AT2G14260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    proline iminopeptidase; PROLINE IMINOPEPTIDASE
    Summary
    encodes proline iminopeptidase
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    Genomic context

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    See PIP in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (6041146..6043974, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ankyrin repeat family protein with DHHC zinc finger domain-containing protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome C oxidase polypeptide VIB family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dual-targeted prolyl aminopeptidase PAP1 is involved in proline accumulation in response to stress and during pollen development. Ghifari AS, et al. J Exp Bot, 2022 Jan 5. PMID 34460901
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001335417.1
    NM_001335418.1
    NM_126994.4
    NM_201725.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to metal ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salt IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    proline iminopeptidase
    NP_179037.2
    • proline iminopeptidase (PIP); FUNCTIONS IN: aminopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S33, proline iminopeptidase 1 (InterPro:IPR005944), Peptidase S33, prolyl aminopeptidase (InterPro:IPR002410), Alpha/beta hydrolase fold-1 (InterPro:IPR000073); Has 7088 Blast hits to 7086 proteins in 1443 species: Archae - 32; Bacteria - 5306; Metazoa - 56; Fungi - 142; Plants - 129; Viruses - 0; Other Eukaryotes - 1423 (source: NCBI BLink).
    NP_973454.1
    • proline iminopeptidase (PIP); FUNCTIONS IN: aminopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S33, proline iminopeptidase 1 (InterPro:IPR005944), Peptidase S33, prolyl aminopeptidase (InterPro:IPR002410), Alpha/beta hydrolase fold-1 (InterPro:IPR000073); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6041146..6043974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126994.4 → NP_179037.2  proline iminopeptidase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179037.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P93732, Q93Y05, Q9SKJ3
      UniProtKB/TrEMBL
      A0A5S9WY15, A0A654ESS0
      Conserved Domains (2) summary
      TIGR01249
      Location:70 → 376
      pro_imino_pep_1; proline iminopeptidase, Neisseria-type subfamily
      pfam00561
      Location:98 → 361
      Abhydrolase_1; alpha/beta hydrolase fold

    2. NM_001335418.1 → NP_001325176.1  proline iminopeptidase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2D9, A0A5S9WY15, A0A654ESS0

    3. NM_001335417.1 → NP_001325175.1  proline iminopeptidase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IFH2, Q941B5

    4. NM_201725.3 → NP_973454.1  proline iminopeptidase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973454.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IFH2, Q941B5
      Conserved Domains (2) summary
      TIGR01249
      Location:19 → 325
      pro_imino_pep_1; proline iminopeptidase, Neisseria-type subfamily
      pfam00561
      Location:47 → 310
      Abhydrolase_1; alpha/beta hydrolase fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P93732.3

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