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    RAB11c RAB GTPase 11C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837490, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB11c
    Official Full Name
    RAB GTPase 11C
    Primary source
    TAIR:AT1G09630
    Locus tag
    AT1G09630
    See related
    Araport:AT1G09630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS RAB GTPASE A2A; ATRAB-A2A; ATRAB11C; ATRABA2A; F21M12.2; F21M12_2; RAB GTPase 11C; RAB GTPASE A2A; RAB-A2A; RAS-RELATED SMALL GTPASE
    Summary
    Encodes a putative GTP-binding protein. Associates with organelles on a pathway from the Golgi to the plasma membrane in interphase. In dividing cells acts at the cell plate.
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    Genomic context

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    See RAB11c in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (3118155..3119815, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glucuronoxylan 4-O-methyltransferase-like protein (DUF579) Neighboring gene ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase Neighboring gene uncharacterized protein Neighboring gene Translation elongation factor EF1B, gamma chain Neighboring gene uncharacterized protein Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The small GTPase RABA2a recruits SNARE proteins to regulate the secretory pathway in parallel with the exocyst complex in Arabidopsis. Pang L, et al. Mol Plant, 2022 Mar 7. PMID 34798312
    2. The caspase-related protease separase (extra spindle poles) regulates cell polarity and cytokinesis in Arabidopsis. Moschou PN, et al. Plant Cell, 2013 Jun. PMID 23898031, Free PMC Article
    3. Rab-A2 and Rab-A3 GTPases define a trans-golgi endosomal membrane domain in Arabidopsis that contributes substantially to the cell plate. Chow CM, et al. Plant Cell, 2008 Jan. PMID 18239134, Free PMC Article
    4. Conserved Arabidopsis ECHIDNA protein mediates trans-Golgi-network trafficking and cell elongation. Gendre D, et al. Proc Natl Acad Sci U S A, 2011 May 10. PMID 21512130, Free PMC Article
    5. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100835.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinesis by cell plate formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell plate IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase 11C
    NP_172434.1
    • RAB GTPase 11C (RAB11c); FUNCTIONS IN: GTP binding; INVOLVED IN: cytokinesis; LOCATED IN: endosome, plasma membrane, cell plate; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab11-related (InterPro:IPR015595); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog A2B (TAIR:AT1G07410.1); Has 27576 Blast hits to 27520 proteins in 758 species: Archae - 26; Bacteria - 154; Metazoa - 14618; Fungi - 3770; Plants - 3044; Viruses - 20; Other Eukaryotes - 5944 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3118155..3119815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100835.3 → NP_172434.1  RAB GTPase 11C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172434.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04486
      UniProtKB/TrEMBL
      A0A178WCS3, A0A5S9THG1, A0A7G2DSE8
      Conserved Domains (1) summary
      PLN03110
      Location:1 → 216
      PLN03110; Rab GTPase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04486.1

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