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    SPR1 spiral1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814896, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPR1
    Official Full Name
    spiral1
    Primary source
    TAIR:AT2G03680
    Locus tag
    AT2G03680
    See related
    Araport:AT2G03680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19B11.13; F19B11_13; SKU6; SPIRAL1
    Summary
    The SPR1 gene encodes a plant-specific 12-kD protein which has a repeated motif at both ends, separated by a predicted rod-like domain, suggesting that it may act as an intermolecular linker. Ubiquitously expressed and belongs to a six-member gene family in Arabidopsis; expressed in transgenic seedlings localized to microtubules within the cortical array, preprophase band, phragmoplast, and mitotic spindle.
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    Genomic context

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    See SPR1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (1120787..1122055)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Asparagine synthase family protein Neighboring gene cell division cycle 48B Neighboring gene ncRNA Neighboring gene coenzyme Q biosynthesis Coq4 family protein / ubiquinone biosynthesis Coq4 family protein Neighboring gene ncRNA Neighboring gene tRNA-Thr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1. Wang S, et al. Plant Cell, 2011 Sep. PMID 21954463, Free PMC Article
    2. Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana. Nakajima K, et al. Plant Cell Physiol, 2006 Apr. PMID 16478750
    3. The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion. Sedbrook JC, et al. Plant Cell, 2004 Jun. PMID 15155883, Free PMC Article
    4. The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis. Wang P, et al. Plant Cell, 2023 Jan 2. PMID 36255272, Free PMC Article
    5. The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana. Furutani I, et al. Development, 2000 Oct. PMID 11003843

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis.
      Title: The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis.
    2. SPR1 and EB1b have complex interactions as they load onto microtubule plus ends and direct polar cell expansion and organ growth in response to directional cues.
      Title: The microtubule plus-end tracking proteins SPR1 and EB1b interact to maintain polar cell elongation and directional organ growth in Arabidopsis.
    3. Salt stress accelerates the 26S proteasome-dependent degradation of SPR1 and facilitates microtubule disassembly and promotes salt stress tolerance.
      Title: Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1.
    4. these observations suggest that SPR1 and SP1Ls act redundantly in maintaining the cortical microtubule organization essential for anisotropic cell growth
      Title: Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana.
    5. Observations suggest that SPR1 is involved in microtubule polymerization dynamics and/or guidance, which in turn influences touch-induced directional cell expansion and axial twisting. [SPIRAL1]
      Title: The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001161019.2
    NM_001335199.1
    NM_126416.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within anisotropic cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cortical microtubule organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with cortical microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cortical microtubule, transverse to long axis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in phragmoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in preprophase band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    spiral1
    NP_001154491.1
    • SPIRAL1 (SPR1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: anisotropic cell growth, unidimensional cell growth; LOCATED IN: spindle microtubule, cortical microtubule, transverse to long axis, preprophase band, phragmoplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; BEST Arabidopsis thaliana protein match is: SPIRAL1-like2 (TAIR:AT1G69230.2); Has 191 Blast hits to 165 proteins in 37 species: Archae - 0; Bacteria - 8; Metazoa - 3; Fungi - 6; Plants - 146; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).
    NP_178464.1
    • SPIRAL1 (SPR1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: anisotropic cell growth, unidimensional cell growth; LOCATED IN: spindle microtubule, cortical microtubule, transverse to long axis, preprophase band, phragmoplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; BEST Arabidopsis thaliana protein match is: SPIRAL1-like2 (TAIR:AT1G69230.2); Has 191 Blast hits to 165 proteins in 37 species: Archae - 0; Bacteria - 8; Metazoa - 3; Fungi - 6; Plants - 146; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1120787..1122055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126416.3 → NP_178464.1  spiral1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178464.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49622, Q9SJW3
      UniProtKB/TrEMBL
      A0A178W0C9, A0A5S9WWX9

    2. NM_001335199.1 → NP_001323957.1  spiral1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49622, Q9SJW3
      UniProtKB/TrEMBL
      A0A178W0C9, A0A5S9WWX9

    3. NM_001161019.2 → NP_001154491.1  spiral1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49622, Q9SJW3
      UniProtKB/TrEMBL
      A0A178W0C9, A0A5S9WWX9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJW3.1

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