U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ELF7 hydroxyproline-rich glycoprotein family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844312, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ELF7
    Official Full Name
    hydroxyproline-rich glycoprotein family protein
    Primary source
    TAIR:AT1G79730
    Locus tag
    AT1G79730
    See related
    Araport:AT1G79730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EARLY FLOWERING 7; F19K16.29; F19K16_29
    Summary
    Encodes a PAF1 homolog that is involved in the control of flowering time by elevating FLC expression to a level that creates the vernalization-responsive, winter-annual habit. Yeast PAF1 is a component of a five-member complex that associates with RNA pol II and is thought to regulate gene expression by recruiting SET1 (a histone 3 Lys 4 [H3-K4] methyl transferase) to the initially transcribed [5'] regions of target chromatin. Mutants display reduced H3-K4 methylation in both FLC and FLM chromatin.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ELF7 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (30000538..30004083, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene ncRNA Neighboring gene hAT transposon superfamily Neighboring gene NADP-malic enzyme 4 Neighboring gene downstream target of AGL15-4

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The SMC5/6 complex recruits the PAF1 complex to facilitate DNA double-strand break repair in Arabidopsis. Li C, et al. EMBO J, 2023 Apr 3. PMID 36815434, Free PMC Article
    2. PAF1-complex-mediated histone methylation of FLOWERING LOCUS C chromatin is required for the vernalization-responsive, winter-annual habit in Arabidopsis. He Y, et al. Genes Dev, 2004 Nov 15. PMID 15520273, Free PMC Article
    3. SKIP Interacts with the Paf1 Complex to Regulate Flowering via the Activation of FLC Transcription in Arabidopsis. Cao Y, et al. Mol Plant, 2015 Dec 7. PMID 26384244
    4. PLANT HOMOLOGOUS TO PARAFIBROMIN is a component of the PAF1 complex and assists in regulating expression of genes within H3K27ME3-enriched chromatin. Park S, et al. Plant Physiol, 2010 Jun. PMID 20363855, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_106622.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    hydroxyproline-rich glycoprotein family protein
    NP_178091.2
    • EARLY FLOWERING 7 (ELF7); CONTAINS InterPro DOMAIN/s: RNA polymerase II-associated, Paf1 (InterPro:IPR007133); Has 76068 Blast hits to 37830 proteins in 1710 species: Archae - 109; Bacteria - 10838; Metazoa - 29407; Fungi - 10155; Plants - 13778; Viruses - 2155; Other Eukaryotes - 9626 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30000538..30004083 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106622.5 → NP_178091.2  hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178091.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HQA1, Q8RW91, Q9CA82, Q9MA04
      UniProtKB/TrEMBL
      A0A178WMB8, A0A5S9WVW9, A0A654EVK8
      Conserved Domains (2) summary
      PRK13831
      Location:104 → 157
      PRK13831; conjugal transfer protein TrbI; Provisional
      pfam03985
      Location:195 → 530
      Paf1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4HQA1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools