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    MT2A metallothionein 2A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820098, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MT2A
    Official Full Name
    metallothionein 2A
    Primary source
    TAIR:AT3G09390
    Locus tag
    AT3G09390
    See related
    Araport:AT3G09390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA METALLOTHIONEIN-1; ARABIDOPSIS THALIANA METALLOTHIONEIN-K; ATMT-1; ATMT-K; metallothionein 2A
    Summary
    metallothionein, binds to and detoxifies excess copper and other metals, limiting oxidative damage
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    Genomic context

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    See MT2A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (2889406..2890574, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene MIP18 family protein Neighboring gene miscRNA Neighboring gene pol-like 3 Neighboring gene Pectinacetylesterase family protein Neighboring gene Pectinacetylesterase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcripts of metallothionein genes in Arabidopsis thaliana. Yeh SC, et al. DNA Seq, 1995. PMID 7612924
    2. Purification and immunological identification of metallothioneins 1 and 2 from Arabidopsis thaliana. Murphy A, et al. Plant Physiol, 1997 Apr. PMID 9112777, Free PMC Article
    3. cDNA Library Screening Identifies Protein Interactors Potentially Involved in Non-Telomeric Roles of Arabidopsis Telomerase. Dokládal L, et al. Front Plant Sci, 2015. PMID 26617625, Free PMC Article
    4. Identification of kinase substrates by bimolecular complementation assays. Pusch S, et al. Plant J, 2012 Apr. PMID 22098373
    5. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337815.1
    NM_111773.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular copper ion homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    metallothionein 2A
    NP_187550.1
    • metallothionein 2A (MT2A); CONTAINS InterPro DOMAIN/s: Plant metallothionein, family 15 (InterPro:IPR000347); BEST Arabidopsis thaliana protein match is: metallothionein 2B (TAIR:AT5G02380.1); Has 597 Blast hits to 588 proteins in 128 species: Archae - 0; Bacteria - 0; Metazoa - 53; Fungi - 2; Plants - 530; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2889406..2890574 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111773.4 → NP_187550.1  metallothionein 2A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187550.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25860, P43391
      UniProtKB/TrEMBL
      A0A178VGL7, A0A5S9XAQ7, A0A7G2EKB2
      Conserved Domains (1) summary
      pfam01439
      Location:7 → 80
      Metallothio_2; Metallothionein

    2. NM_001337815.1 → NP_001327181.1  metallothionein 2A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25860, P43391
      UniProtKB/TrEMBL
      A0A178VGL7, A0A5S9XAQ7, A0A7G2EKB2
      Conserved Domains (1) summary
      pfam01439
      Location:7 → 80
      Metallothio_2; Metallothionein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25860.2

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