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    CASP CCAAT-displacement protein alternatively spliced product [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821377, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CASP
    Official Full Name
    CCAAT-displacement protein alternatively spliced product
    Primary source
    TAIR:AT3G18480
    Locus tag
    AT3G18480
    See related
    Araport:AT3G18480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtCASP; CCAAT-displacement protein alternatively spliced product
    Summary
    This gene is predicted to encode a protein that functions as a Golgi apparatus structural component, known as a golgin in mammals and yeast. A fluorescently-tagged version of CASP co-localizes with Golgi markers, and this localization appears to require the C-terminal (565#Aei689aa) portion of the protein. The protein is inserted into a membrane in a type II orientation.
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    Genomic context

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    See CASP in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Sequence:
    Chromosome: 3; NC_003074.8 (6336692..6341788)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene PLAC8 family protein Neighboring gene PLAC8 family protein Neighboring gene iaa-leucine resistant 2 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of AtCASP, a plant transmembrane Golgi matrix protein. Renna L, et al. Plant Mol Biol, 2005 May. PMID 16028120
    2. Fluorescence lifetime imaging of interactions between Golgi tethering factors and small GTPases in plants. Osterrieder A, et al. Traffic, 2009 Aug. PMID 19490533
    3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112733.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    CCAAT-displacement protein alternatively spliced product
    NP_566611.1
    • CCAAT-displacement protein alternatively spliced product (CASP); INVOLVED IN: intra-Golgi vesicle-mediated transport; LOCATED IN: integral to membrane, Golgi apparatus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CASP, C-terminal (InterPro:IPR012955); Has 108439 Blast hits to 62245 proteins in 2877 species: Archae - 1242; Bacteria - 16953; Metazoa - 49041; Fungi - 8922; Plants - 5181; Viruses - 394; Other Eukaryotes - 26706 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6336692..6341788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112733.3 → NP_566611.1  CCAAT-displacement protein alternatively spliced product [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566611.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZW7, Q9LS42
      UniProtKB/TrEMBL
      A0A5S9XDV8, A0A654F8F9
      Conserved Domains (2) summary
      TIGR02168
      Location:130 → 432
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam08172
      Location:438 → 667
      CASP_C; CASP C terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LS42.2

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