U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SPPL4 SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839499, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SPPL4
    Official Full Name
    SIGNAL PEPTIDE PEPTIDASE-LIKE 4
    Primary source
    TAIR:AT1G01650
    Locus tag
    AT1G01650
    See related
    Araport:AT1G01650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SIGNAL PEPTIDE PEPTIDASE-LIKE 4; ATSPPL4; SIGNAL PEPTIDE PEPTIDASE-LIKE 4; T1N6.3; T1N6_3
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SPPL4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (232840..237905, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene plasma membrane intrinsic protein 1C Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene BTB/POZ domain-containing protein Neighboring gene miscRNA Neighboring gene RING/U-box superfamily protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, et al. Dev Cell, 2014 May 12. PMID 24823379
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001035853.1
    NM_001331286.1
    NM_001331287.1
    NM_100047.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    SIGNAL PEPTIDE PEPTIDASE-LIKE 4
    NP_001318903.1
    • SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (SPPL4); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (TAIR:AT1G63690.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_171671.2
    • SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (SPPL4); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (TAIR:AT1G63690.1); Has 1466 Blast hits to 1433 proteins in 284 species: Archae - 0; Bacteria - 176; Metazoa - 611; Fungi - 153; Plants - 303; Viruses - 0; Other Eukaryotes - 223 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      232840..237905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100047.4 → NP_171671.2  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171671.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WMJ8, Q9LQ94
      UniProtKB/TrEMBL
      A0A178WKW5, A0A178WMP2, A0A5S9S329
      Conserved Domains (2) summary
      pfam04258
      Location:241 → 527
      Peptidase_A22B; Signal peptide peptidase
      cl28883
      Location:46 → 183
      PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...

    2. NM_001035853.1 → NP_001030930.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030930.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44
      Conserved Domains (2) summary
      pfam04258
      Location:99 → 385
      Peptidase_A22B; Signal peptide peptidase
      cl10459
      Location:1 → 41
      Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

    3. NM_001331286.1 → NP_001318903.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44

    4. NM_001331287.1 → NP_001323100.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WMJ8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.