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    U2B'' U2 small nuclear ribonucleoprotein B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817576, updated on 18-Sep-2024

    Summary

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    Official Symbol
    U2B''
    Official Full Name
    U2 small nuclear ribonucleoprotein B
    Primary source
    TAIR:AT2G30260
    Locus tag
    AT2G30260
    See related
    Araport:AT2G30260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T9D9.7; T9D9_7; U2 small nuclear ribonucleoprotein B
    Summary
    encodes U2B'', which is a component of the U2 snRNP complex. Its precise role in pre-mRNA splicing is still unknown. It has been suggested that U2B0 may not be required for the splicing reaction itself but may have a role in U2 snRNP biogenesis. Deletion analysis of the U2B0 gene fusion has identified the N-terminal RNP-80 motif as sufficient for localization to the coiled body and the nucleus.
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    Genomic context

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    See U2B'' in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (12905345..12907665, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cation/hydrogen exchanger family protein Neighboring gene WRKY DNA-binding protein 25 Neighboring gene LURP-one-like protein (DUF567) Neighboring gene RNA-directed DNA methylation 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The movement of coiled bodies visualized in living plant cells by the green fluorescent protein. Boudonck K, et al. Mol Biol Cell, 1999 Jul. PMID 10397766, Free PMC Article
    2. A distant coilin homologue is required for the formation of cajal bodies in Arabidopsis. Collier S, et al. Mol Biol Cell, 2006 Jul. PMID 16624863, Free PMC Article
    3. Coiled body numbers in the Arabidopsis root epidermis are regulated by cell type, developmental stage and cell cycle parameters. Boudonck K, et al. J Cell Sci, 1998 Dec 18. PMID 9819359
    4. Evolutionary conservation of minor U12-type spliceosome between plants and humans. Lorkovic ZJ, et al. RNA, 2005 Jul. PMID 15987817, Free PMC Article
    5. Use of fluorescent protein tags to study nuclear organization of the spliceosomal machinery in transiently transformed living plant cells. Lorković ZJ, et al. Mol Biol Cell, 2004 Jul. PMID 15133128, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336249.1
    NM_128579.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cis assembly of pre-catalytic spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Cajal body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U2 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    U2 small nuclear ribonucleoprotein B
    NP_180585.1
    • U2 small nuclear ribonucleoprotein B (U2B''); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: cis assembly of pre-catalytic spliceosome; LOCATED IN: nucleoplasm, Cajal body, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT1G06960.1); Has 1885 Blast hits to 1858 proteins in 260 species: Archae - 0; Bacteria - 2; Metazoa - 926; Fungi - 414; Plants - 327; Viruses - 1; Other Eukaryotes - 215 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12905345..12907665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128579.4 → NP_180585.1  U2 small nuclear ribonucleoprotein B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180585.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22922, Q8LB63
      UniProtKB/TrEMBL
      A0A178VQB8, A0A654F858
      Conserved Domains (2) summary
      cd12246
      Location:12 → 88
      RRM1_U1A_like; RNA recognition motif 1 in the U1A/U2B"/SNF protein family
      cd12247
      Location:156 → 228
      RRM2_U1A_like; RNA recognition motif 2 in the U1A/U2B"/SNF protein family

    2. NM_001336249.1 → NP_001324159.1  U2 small nuclear ribonucleoprotein B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRW1, A0A1P8AZB8, A0A384K9Y7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22922.1

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