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    AMP-dependent synthetase and ligase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827639, updated on 18-Sep-2024

    Summary

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    Official Full Name
    AMP-dependent synthetase and ligase family protein
    Primary source
    TAIR:AT4G19010
    Locus tag
    AT4G19010
    See related
    Araport:AT4G19010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13C5.180; F13C5_180
    Summary
    Encodes for a 4-coumarate-CoA ligase involved in the biosynthesis of the benzenoid ring of ubiquinone from phenylalanine.
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (10411466..10414324, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene xyloglucan endotransglucosylase/hydrolase 29 Neighboring gene Transcription elongation factor (TFIIS) family protein Neighboring gene E2F/DP family winged-helix DNA-binding domain-containing protein Neighboring gene Proteasome component (PCI) domain protein Neighboring gene chromomethylase 2 Neighboring gene NOD26-like major intrinsic protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Origin and Biosynthesis of the Benzenoid Moiety of Ubiquinone (Coenzyme Q) in Arabidopsis. Block A, et al. Plant Cell, 2014 May. PMID 24838974, Free PMC Article
    2. Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana. Kienow L, et al. J Exp Bot, 2008. PMID 18267944
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_118019.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-coumarate-CoA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 4-coumarate-CoA ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables 4-hydroxybenzoate-CoA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables CoA-ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in response to bacterium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AMP-dependent synthetase and ligase family protein
    NP_193636.1
    • AMP-dependent synthetase and ligase family protein; FUNCTIONS IN: 4-coumarate-CoA ligase activity; INVOLVED IN: metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: OPC-8:0 CoA ligase1 (TAIR:AT1G20510.1); Has 83687 Blast hits to 76218 proteins in 3879 species: Archae - 1158; Bacteria - 54713; Metazoa - 3437; Fungi - 4716; Plants - 2771; Viruses - 1; Other Eukaryotes - 16891 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10411466..10414324 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118019.3 → NP_193636.1  AMP-dependent synthetase and ligase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49414, Q84P24, Q8GYV8
      UniProtKB/TrEMBL
      A0A178V1G1, A0A7G2F4C2
      Conserved Domains (1) summary
      PLN02574
      Location:9 → 566
      PLN02574; 4-coumarate--CoA ligase-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84P24.2

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