OS9 ER lectin-like protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: OS9
Official Full Name: ER lectin-like protein
Primary source: TAIR:AT5G35080
Locus tag: AT5G35080
See related: Araport:AT5G35080
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtOS9; F7N22.4; F7N22_4
Summary: Encodes a protein involved in the endoplasmic reticulum-associated degradation of glycoproteins.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See OS9 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 8

Sequence:: Chromosome: 5; NC_003076.8 (13354156..13356884, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

UBC32 negatively controls the stability of AtOS9, a component in the HRD1 complex.
Title: ERAD Tuning of the HRD1 Complex Component AtOS9 Is Modulated by an ER-Bound E2, UBC32.
a functional role of AtOS9 in a plant ERAD process that degrades misfolded receptor-like kinases
Title: The Arabidopsis homolog of the mammalian OS-9 protein plays a key role in the endoplasmic reticulum-associated degradation of misfolded receptor-like kinases.
OS9 is a component of the plant endoplasmic reticulum-associated degradation machinery and may act specifically in the glycoprotein degradation pathway.[OS9]
Title: Unraveling the function of Arabidopsis thaliana OS9 in the endoplasmic reticulum-associated degradation of glycoproteins.

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

NM_122899.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within ERAD pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within ERAD pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endoplasmic reticulum unfolded protein response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: ER lectin-like protein

NP_568525.1

INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mannose-6-phosphate receptor, binding (InterPro:IPR009011), Glucosidase II beta subunit-like (InterPro:IPR012913); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

13354156..13356884 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_122899.3 → NP_568525.1 ER lectin-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_568525.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O65221, Q8GWH3, Q8LD14

UniProtKB/TrEMBL

A0A178UMY2, A0A7G2FIB7

Conserved Domains (1) summary

pfam07915
Location:121 → 194

PRKCSH; Glucosidase II beta subunit-like protein