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    Bbx bobby sox HMG box containing [ Mus musculus (house mouse) ]

    Gene ID: 70508, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bbxprovided by MGI
    Official Full Name
    bobby sox HMG box containingprovided by MGI
    Primary source
    MGI:MGI:1917758
    See related
    Ensembl:ENSMUSG00000022641 AllianceGenome:MGI:1917758
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5530401J07Rik; 5730403O13Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within bone development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human BBX (BBX high mobility group box domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in placenta adult (RPKM 16.6), testis adult (RPKM 10.8) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Bbx in Genome Data Viewer
    Location:
    16 B5; 16 31.35 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (50012207..50252829, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (50191844..50432466, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4827 Neighboring gene predicted gene, 32101 Neighboring gene STARR-seq mESC enhancer starr_40979 Neighboring gene STARR-seq mESC enhancer starr_40980 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_40982 Neighboring gene STARR-seq mESC enhancer starr_40984 Neighboring gene STARR-seq mESC enhancer starr_40987 Neighboring gene STARR-positive B cell enhancer mm9_chr16:50432445-50432746 Neighboring gene STARR-seq mESC enhancer starr_40989 Neighboring gene STARR-seq mESC enhancer starr_40990 Neighboring gene predicted gene, 32231 Neighboring gene predicted gene, 41459

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex. Sánchez-Díaz A, et al. Curr Genet, 2001 Sep. PMID 11680820
    2. Nuclear factor one X regulates Bobby sox during development of the mouse forebrain. Dixon C, et al. Cell Mol Neurobiol, 2013 Oct. PMID 23852417
    3. Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic. Chen T, et al. Dev Genes Evol, 2014 Dec. PMID 25079045
    4. A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitative trait locus. Baguet A, et al. J Exp Med, 2004 Dec 20. PMID 15596523, Free PMC Article
    5. Bobby sox homolog regulates tooth root formation through modulation of dentin sialophosphoprotein. Ihn HJ, et al. J Cell Physiol, 2021 Jan. PMID 32537777

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Immunohistochemistry analysis in mouse brain revealed that BBX was weakly expressed in the cerebellum and highly expressed in the cortex and hippocampus.
      Title: Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic.
    2. Bbx is a downstream target of NFIX during development of the forebrain.
      Title: Nuclear factor one X regulates Bobby sox during development of the mouse forebrain.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (3)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within bone development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HMG box transcription factor BBX
    Names
    HMG box-containing protein 2
    bobby sox homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347240.1 → NP_001334169.1  HMG box transcription factor BBX isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154781, AK029747, CT571273
      Consensus CDS
      CCDS84241.1
      UniProtKB/Swiss-Prot
      Q8VBW5
      Related
      ENSMUSP00000086826.4, ENSMUST00000089404.10
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    2. NM_027444.3 → NP_081720.2  HMG box transcription factor BBX isoform 1

      See identical proteins and their annotated locations for NP_081720.2

      Status: VALIDATED

      Source sequence(s)
      AC109627, AC113067, AC154781, CT571273
      Consensus CDS
      CCDS37354.1
      UniProtKB/Swiss-Prot
      B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
      Related
      ENSMUSP00000119238.2, ENSMUST00000138166.8
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      50012207..50252829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249277.2 → XP_030105137.1  HMG box transcription factor BBX isoform X3

      UniProtKB/Swiss-Prot
      B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    2. XM_011246009.3 → XP_011244311.1  HMG box transcription factor BBX isoform X5

      See identical proteins and their annotated locations for XP_011244311.1

      UniProtKB/Swiss-Prot
      Q8VBW5
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    3. XM_006522546.3 → XP_006522609.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522609.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    4. XM_017317130.3 → XP_017172619.1  HMG box transcription factor BBX isoform X3

      UniProtKB/Swiss-Prot
      B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    5. XM_030249281.2 → XP_030105141.1  HMG box transcription factor BBX isoform X6

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 295
      DUF2028; Domain of unknown function (DUF2028)

    6. XM_011246008.4 → XP_011244310.1  HMG box transcription factor BBX isoform X3

      See identical proteins and their annotated locations for XP_011244310.1

      UniProtKB/Swiss-Prot
      B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
      Related
      ENSMUSP00000110132.2, ENSMUST00000114488.8
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    7. XM_006522549.5 → XP_006522612.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522612.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    8. XM_030249275.2 → XP_030105135.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    9. XM_006522547.5 → XP_006522610.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522610.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    10. XM_036160122.1 → XP_036016015.1  HMG box transcription factor BBX isoform X2

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 295
      DUF2028; Domain of unknown function (DUF2028)

    11. XM_036160123.1 → XP_036016016.1  HMG box transcription factor BBX isoform X2

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 295
      DUF2028; Domain of unknown function (DUF2028)

    12. XM_036160118.1 → XP_036016011.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    13. XM_006522544.5 → XP_006522607.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522607.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    14. XM_006522545.5 → XP_006522608.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522608.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    15. XM_006522554.5 → XP_006522617.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522617.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    16. XM_036160120.1 → XP_036016013.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    17. XM_011246006.4 → XP_011244308.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_011244308.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    18. XM_036160126.1 → XP_036016019.1  HMG box transcription factor BBX isoform X7

      Related
      ENSMUSP00000066384.7, ENSMUST00000066037.13
      Conserved Domains (2) summary
      cd01388
      Location:54 → 112
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:152 → 257
      DUF2028; Domain of unknown function (DUF2028)

    19. XM_030249278.2 → XP_030105138.1  HMG box transcription factor BBX isoform X4

      Conserved Domains (2) summary
      cd01388
      Location:54 → 112
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:152 → 284
      DUF2028; Domain of unknown function (DUF2028)

    20. XM_011246005.4 → XP_011244307.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_011244307.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    21. XM_006522543.5 → XP_006522606.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522606.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    22. XM_006522553.5 → XP_006522616.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522616.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    23. XM_036160121.1 → XP_036016014.1  HMG box transcription factor BBX isoform X2

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 295
      DUF2028; Domain of unknown function (DUF2028)

    24. XM_006522561.5 → XP_006522624.1  HMG box transcription factor BBX isoform X4

      See identical proteins and their annotated locations for XP_006522624.1

      Conserved Domains (2) summary
      cd01388
      Location:54 → 112
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:152 → 284
      DUF2028; Domain of unknown function (DUF2028)

    25. XM_006522560.5 → XP_006522623.1  HMG box transcription factor BBX isoform X4

      See identical proteins and their annotated locations for XP_006522623.1

      Conserved Domains (2) summary
      cd01388
      Location:54 → 112
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:152 → 284
      DUF2028; Domain of unknown function (DUF2028)

    26. XM_011246007.4 → XP_011244309.1  HMG box transcription factor BBX isoform X2

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 295
      DUF2028; Domain of unknown function (DUF2028)

    27. XM_006522555.5 → XP_006522618.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522618.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    28. XM_030249279.2 → XP_030105139.1  HMG box transcription factor BBX isoform X4

      Conserved Domains (2) summary
      cd01388
      Location:54 → 112
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:152 → 284
      DUF2028; Domain of unknown function (DUF2028)

    29. XM_036160116.1 → XP_036016009.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    30. XM_030249274.2 → XP_030105134.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    31. XM_036160117.1 → XP_036016010.1  HMG box transcription factor BBX isoform X1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    32. XM_006522548.5 → XP_006522611.1  HMG box transcription factor BBX isoform X1

      See identical proteins and their annotated locations for XP_006522611.1

      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)

    33. XM_036160125.1 → XP_036016018.1  HMG box transcription factor BBX isoform X5

      Related
      ENSMUSP00000086821.5, ENSMUST00000089399.11
      Conserved Domains (2) summary
      cd01388
      Location:79 → 150
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam09667
      Location:190 → 322
      DUF2028; Domain of unknown function (DUF2028)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VBW5.2 GenPept UniProtKB/Swiss-Prot:Q8VBW5

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