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    CKA3 Protein kinase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816838, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CKA3
    Official Full Name
    Protein kinase superfamily protein
    Primary source
    TAIR:AT2G23080
    Locus tag
    AT2G23080
    See related
    Araport:AT2G23080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha chain 3; casein kinase II; F21P24.14; F21P24_14
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    Genomic context

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    See CKA3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Sequence:
    Chromosome: 2; NC_003071.7 (9827104..9829537)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Putative membrane lipoprotein Neighboring gene Protein kinase superfamily protein Neighboring gene Uncharacterized protein family SERF Neighboring gene ncRNA Neighboring gene Major facilitator superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CK2-defective Arabidopsis plants exhibit enhanced double-strand break repair rates and reduced survival after exposure to ionizing radiation. Moreno-Romero J, et al. Plant J, 2012 Aug. PMID 22487192
    2. Casein kinase II α subunits affect multiple developmental and stress-responsive pathways in Arabidopsis. Mulekar JJ, et al. Plant J, 2012 Jan. PMID 21950772
    3. A role for protein kinase casein kinase2 α-subunits in the Arabidopsis circadian clock. Lu SX, et al. Plant Physiol, 2011 Nov. PMID 21900482, Free PMC Article
    4. The p23 co-chaperone protein is a novel substrate of CK2 in Arabidopsis. Tosoni K, et al. Mol Cell Biochem, 2011 Oct. PMID 21735091
    5. An extensive survey of CK2 alpha and beta subunits in Arabidopsis: multiple isoforms exhibit differential subcellular localization. Salinas P, et al. Plant Cell Physiol, 2006 Sep. PMID 16926165

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CK2 alpha subunits affect diverse developmental and stress responsive pathways in Arabidopsis.
      Title: Casein kinase II α subunits affect multiple developmental and stress-responsive pathways in Arabidopsis.
    2. CK2 alpha subunits are important components of the Arabidopsis circadian system and their effects on rhythms are in part due to their phosphorylation of CIRCADIAN CLOCK ASSOCIATED1. [CKa3]
      Title: A role for protein kinase casein kinase2 α-subunits in the Arabidopsis circadian clock.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127872.4
    NM_201789.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within chromatin organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within chromatin organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within circadian rhythm IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell cycle IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV-C IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to gamma radiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein kinase superfamily protein
    NP_179890.1
    • Protein kinase superfamily protein; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: casein kinase alpha 1 (TAIR:AT5G67380.1); Has 85082 Blast hits to 84212 proteins in 2506 species: Archae - 72; Bacteria - 10027; Metazoa - 32503; Fungi - 11396; Plants - 13810; Viruses - 302; Other Eukaryotes - 16972 (source: NCBI BLink).
    NP_973518.1
    • Protein kinase superfamily protein; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: casein kinase alpha 1 (TAIR:AT5G67380.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9827104..9829537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127872.4 → NP_179890.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179890.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4ILF5, O64817, Q8L5T7
      UniProtKB/TrEMBL
      A0A178VTA8, A0A5S9X0I4, A0A7G2EED0
      Conserved Domains (1) summary
      cd14132
      Location:15 → 319
      STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

    2. NM_201789.2 → NP_973518.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EED0
      Conserved Domains (1) summary
      cd14132
      Location:15 → 298
      STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64817.1

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