KCS8 3-ketoacyl-CoA synthase 8 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: KCS8
Official Full Name: 3-ketoacyl-CoA synthase 8
Primary source: TAIR:AT2G15090
Locus tag: AT2G15090
See related: Araport:AT2G15090
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 3-ketoacyl-CoA synthase 8; T15J14.13; T15J14_13
Summary: Encodes KCS8, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

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NM_127071.3

Function	Evidence Code	Pubs
enables fatty acid elongase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within fatty acid elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within very long-chain fatty acid metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

NP_179113.2

3-ketoacyl-CoA synthase 8 (KCS8); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: fatty acid elongation, very long-chain fatty acid metabolic process, response to osmotic stress; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 16 (TAIR:AT4G34250.1); Has 4430 Blast hits to 4415 proteins in 1092 species: Archae - 0; Bacteria - 1687; Metazoa - 0; Fungi - 24; Plants - 2579; Viruses - 0; Other Eukaryotes - 140 (source: NCBI BLink).