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    PAO4 polyamine oxidase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842894, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAO4
    Official Full Name
    polyamine oxidase 4
    Primary source
    TAIR:AT1G65840
    Locus tag
    AT1G65840
    See related
    Araport:AT1G65840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPAO4; F1E22.18; F1E22_18; polyamine oxidase 4
    Summary
    encodes a peroxisomal polyamine oxidase, involved in the back-conversion polyamine degradation pathway. Among the five polyamine oxidases in the Arabidopsis genome, PAO4 is the major isoform in root peroxisomes.
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    Genomic context

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    See PAO4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (24489758..24493077)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene microsomal glutathione s-transferase Neighboring gene tRNA-Ser Neighboring gene uncharacterized protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene flavin-monooxygenase glucosinolate S-oxygenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana. Kamada-Nobusada T, et al. Plant Cell Physiol, 2008 Sep. PMID 18703589
    2. Characterization of five polyamine oxidase isoforms in Arabidopsis thaliana. Takahashi Y, et al. Plant Cell Rep, 2010 Sep. PMID 20532512
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The peroxisomal AtPAO4 enzyme plays a role in polyamine catabolism and homeostasis, especially in roots.
      Title: A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_105256.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables polyamine oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables spermine oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within polyamine catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within polyamine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermidine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    polyamine oxidase 4
    NP_176759.1
    • polyamine oxidase 4 (PAO4); CONTAINS InterPro DOMAIN/s: Amine oxidase (InterPro:IPR002937), Flavin-containing amine oxidase (InterPro:IPR001613); BEST Arabidopsis thaliana protein match is: polyamine oxidase 3 (TAIR:AT3G59050.1); Has 7028 Blast hits to 6613 proteins in 1153 species: Archae - 127; Bacteria - 2858; Metazoa - 1453; Fungi - 590; Plants - 766; Viruses - 0; Other Eukaryotes - 1234 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24489758..24493077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105256.4 → NP_176759.1  polyamine oxidase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176759.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H191, Q94JZ7, Q9SHX4
      UniProtKB/TrEMBL
      A0A178WKV9, A0A5S9WTH5
      Conserved Domains (1) summary
      PLN02268
      Location:29 → 464
      PLN02268; probable polyamine oxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H191.1

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