KCS1 3-ketoacyl-CoA synthase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: KCS1
Official Full Name: 3-ketoacyl-CoA synthase 1
Primary source: TAIR:AT1G01120
Locus tag: AT1G01120
See related: Araport:AT1G01120
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 3-ketoacyl-CoA synthase 1; T25K16.11; T25K16_11
Summary: Encodes a condensing enzyme KCS1 (3-ketoacyl-CoA synthase 1) which is involved in the critical fatty acid elongation process in wax biosynthesis.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

AKR2A interacts with KCS1 to improve VLCFAs contents and chilling tolerance of Arabidopsis thaliana.
Title: AKR2A interacts with KCS1 to improve VLCFAs contents and chilling tolerance of Arabidopsis thaliana.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_099994.4

Function	Evidence Code	Pubs
enables fatty acid elongase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to cold	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cutin-based cuticle development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within fatty acid elongation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to cold	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within very long-chain fatty acid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within very long-chain fatty acid metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within wax biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within wax biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytosolic ribosome	HDA more info	PubMed
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NP_171620.2

3-ketoacyl-CoA synthase 1 (KCS1); FUNCTIONS IN: fatty acid elongase activity, acyltransferase activity; INVOLVED IN: in 7 processes; LOCATED IN: cytosolic ribosome, endoplasmic reticulum, membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 11 (TAIR:AT2G26640.1); Has 3961 Blast hits to 3946 proteins in 966 species: Archae - 0; Bacteria - 1388; Metazoa - 0; Fungi - 5; Plants - 2408; Viruses - 0; Other Eukaryotes - 160 (source: NCBI BLink).