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    SYP43 syntaxin of plants 43 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819740, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SYP43
    Official Full Name
    syntaxin of plants 43
    Primary source
    TAIR:AT3G05710
    Locus tag
    AT3G05710
    See related
    Araport:AT3G05710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSYP43; F18C1.2; F18C1_2; syntaxin of plants 43
    Summary
    Encodes a member of SYP4 Gene Family that is a plant ortholog of the Tlg2/syntaxin16 Qa-SNARE. Together with SYP42, it regulates the secretory and vacuolar transport pathways in the post-Golgi network and maintains the morphology of the Golgi apparatus and TGN and is required for extracellular resistance responses to a fungal pathogen.
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    Genomic context

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    See SYP43 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (1684946..1687664)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene nuclear factor Y, subunit A2 Neighboring gene Drought-responsive family protein Neighboring gene ncRNA Neighboring gene importin alpha isoform 7 Neighboring gene hypothetical protein (DUF3511) Neighboring gene S locus-related glycoprotein 1 (SLR1) binding pollen coat protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Qa-SNAREs localized to the trans-Golgi network regulate multiple transport pathways and extracellular disease resistance in plants. Uemura T, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307646, Free PMC Article
    2. Functional redundancy between trans-Golgi network SNARE family members in Arabidopsis thaliana. Kim SJ, et al. BMC Biochem, 2013 Sep 11. PMID 24021022, Free PMC Article
    3. Interactions between syntaxins identify at least five SNARE complexes within the Golgi/prevacuolar system of the Arabidopsis cell. Sanderfoot AA, et al. Mol Biol Cell, 2001 Dec. PMID 11739776, Free PMC Article
    4. The Arabidopsis genome. An abundance of soluble N-ethylmaleimide-sensitive factor adaptor protein receptors. Sanderfoot AA, et al. Plant Physiol, 2000 Dec. PMID 11115874, Free PMC Article
    5. Label-free protein quantification for plant Golgi protein localization and abundance. Nikolovski N, et al. Plant Physiol, 2014 Oct. PMID 25122472, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111445.5
    NM_180188.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SNAP receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in Golgi to plasma membrane protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in Golgi to vacuole transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular protein transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within membrane fusion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within protein secretion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of defense response to fungus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in salicylic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in trans-Golgi network membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within vacuolar transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in vesicle fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    syntaxin of plants 43
    NP_566256.1
    • syntaxin of plants 43 (SYP43); FUNCTIONS IN: SNAP receptor activity; INVOLVED IN: intracellular protein transport, cellular membrane fusion; LOCATED IN: membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), t-SNARE (InterPro:IPR010989), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), Syntaxin, N-terminal (InterPro:IPR006011); BEST Arabidopsis thaliana protein match is: syntaxin of plants 41 (TAIR:AT5G26980.2); Has 2057 Blast hits to 2057 proteins in 255 species: Archae - 6; Bacteria - 12; Metazoa - 861; Fungi - 474; Plants - 365; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_850519.1
    • syntaxin of plants 43 (SYP43); FUNCTIONS IN: SNAP receptor activity; INVOLVED IN: intracellular protein transport, cellular membrane fusion; LOCATED IN: membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Target SNARE coiled-coil domain (InterPro:IPR000727), t-SNARE (InterPro:IPR010989), Syntaxin/epimorphin, conserved site (InterPro:IPR006012), Syntaxin, N-terminal (InterPro:IPR006011); BEST Arabidopsis thaliana protein match is: syntaxin of plants 41 (TAIR:AT5G26980.2); Has 2056 Blast hits to 2056 proteins in 255 species: Archae - 6; Bacteria - 12; Metazoa - 855; Fungi - 475; Plants - 368; Viruses - 0; Other Eukaryotes - 340 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1684946..1687664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111445.5 → NP_566256.1  syntaxin of plants 43 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566256.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V4W5
      Conserved Domains (2) summary
      smart00503
      Location:84 → 192
      SynN; Syntaxin N-terminal domain
      cd15845
      Location:239 → 295
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    2. NM_180188.3 → NP_850519.1  syntaxin of plants 43 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850519.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L7J6, Q9M9X6, Q9SUJ1
      UniProtKB/TrEMBL
      A0A178V6F2, A0A5S9X9R2, A0A654F4F2
      Conserved Domains (1) summary
      COG5325
      Location:81 → 327
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SUJ1.2

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