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    PDIL1-6 PDI-like 1-6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820856, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PDIL1-6
    Official Full Name
    PDI-like 1-6
    Primary source
    TAIR:AT3G16110
    Locus tag
    AT3G16110
    See related
    Araport:AT3G16110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 4; ATPDI4; ATPDIL1-6; PDI-like 1-6; PDI4; PROTEIN DISULFIDE ISOMERASE 4
    Summary
    Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Unlike several other PDI family members, transcript levels for this gene are not up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin).
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    Genomic context

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    See PDIL1-6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (5460793..5463899, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Zinc-binding ribosomal protein family protein Neighboring gene RING/U-box superfamily protein Neighboring gene RAB GTPase homolog G3C Neighboring gene uncharacterized protein Neighboring gene Dynein light chain type 1 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase genes and AtbZIP60 modulates the response in Arabidopsis thaliana. Lu DP, et al. Mol Genet Genomics, 2008 Sep. PMID 18574595
    2. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_112481.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein disulfide isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    PDI-like 1-6
    NP_188232.2
    • PDI-like 1-6 (PDIL1-6); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: cell redox homeostasis; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 1-5 (TAIR:AT1G52260.1); Has 9564 Blast hits to 7390 proteins in 1532 species: Archae - 71; Bacteria - 3133; Metazoa - 2543; Fungi - 813; Plants - 1159; Viruses - 1; Other Eukaryotes - 1844 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5460793..5463899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112481.4 → NP_188232.2  PDI-like 1-6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188232.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YD5, Q66GQ3, Q9LW75
      UniProtKB/TrEMBL
      A0A178VNL8, A0A5S9XCY6
      Conserved Domains (1) summary
      TIGR01130
      Location:77 → 522
      ER_PDI_fam; protein disulfide isomerase, eukaryotic
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66GQ3.1

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