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    RST1 ARM repeat superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822389, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RST1
    Official Full Name
    ARM repeat superfamily protein
    Primary source
    TAIR:AT3G27670
    Locus tag
    AT3G27670
    See related
    Araport:AT3G27670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RESURRECTION1
    Summary
    A novel protein, did not show high similarity to any protein of known function; reveals a novel genetic connection between lipid synthesis and embryo development. Expressed in all tissues examined including leaves, flowers, roots, stems, and siliques, but accumulation levels were not correlated with the degree to which different organs appeared affected by the mutation. Mutant plants showed alterations in the cuticular wax profiles and embryo development.
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    Genomic context

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    See RST1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    21
    Sequence:
    Chromosome: 3; NC_003074.8 (10245112..10253308)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene LOB domain-containing protein 25 Neighboring gene oleosin 4 Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene photosystem II light harvesting complex protein 2.3 Neighboring gene zinc finger (CCCH-type) family protein / RNA recognition motif (RRM)-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis RESURRECTION1 gene regulates a novel antagonistic interaction in plant defense to biotrophs and necrotrophs. Mang HG, et al. Plant Physiol, 2009 Sep. PMID 19625635, Free PMC Article
    2. Mutation of the RESURRECTION1 locus of Arabidopsis reveals an association of cuticular wax with embryo development. Chen X, et al. Plant Physiol, 2005 Oct. PMID 16183838, Free PMC Article
    3. RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis. Lange H, et al. Nat Commun, 2019 Aug 27. PMID 31455787, Free PMC Article
    4. RST1 Is a FREE1 Suppressor That Negatively Regulates Vacuolar Trafficking in Arabidopsis. Zhao Q, et al. Plant Cell, 2019 Sep. PMID 31221737, Free PMC Article
    5. A genetics screen highlights emerging roles for CPL3, RST1 and URT1 in RNA metabolism and silencing. Li T, et al. Nat Plants, 2019 May. PMID 31076735

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RST1 is a negative regulator controlling membrane protein homeostasis and FREE1-mediated functions in plants.
      Title: RST1 Is a FREE1 Suppressor That Negatively Regulates Vacuolar Trafficking in Arabidopsis.
    2. RST1 and RST1 INTERACTING PROTEIN (RIPR) connect the cytosolic Arabidopsis RNA exosome to the Ski complex. rst1 and ripr mutants accumulate RNA quality control siRNAs produced by the post-transcriptional gene silencing machinery when mRNA degradation is compromised. Study biochemical and genetic data establish RST1 and RIPR as cofactors of the cytoplasmic exosome and the Ski complex in plants.
      Title: RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis.
    3. role in RNA metabolism and silencing
      Title: A genetics screen highlights emerging roles for CPL3, RST1 and URT1 in RNA metabolism and silencing.
    4. A mutation in RST1 defines a unique combination of disease responses to biotrophic and necrotrophic fungi in that it antagonizes salicylic acid-dependent defense and enhances JA-mediated defense through a mechanism that also controls cuticle synthesis.
      Title: The Arabidopsis RESURRECTION1 gene regulates a novel antagonistic interaction in plant defense to biotrophs and necrotrophs.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_113683.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in alkane biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cutin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of post-transcriptional gene silencing by regulatory ncRNA IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in seed development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within wax biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ARM repeat superfamily protein
    NP_189404.2
    • RESURRECTION1 (RST1); FUNCTIONS IN: binding; INVOLVED IN: cuticle hydrocarbon biosynthetic process, embryo development ending in seed dormancy; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-type fold (InterPro:IPR016024); Has 92 Blast hits to 88 proteins in 41 species: Archae - 0; Bacteria - 0; Metazoa - 50; Fungi - 0; Plants - 29; Viruses - 0; Other Eukaryotes - 13 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10245112..10253308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113683.3 → NP_189404.2  ARM repeat superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189404.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IWL6, Q7XZF5, Q9LVX3
      UniProtKB/TrEMBL
      A0A178V799, A0A654FCN5
      Conserved Domains (1) summary
      pfam12530
      Location:554 → 750
      DUF3730; Protein of unknown function (DUF3730)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7XZF5.2

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