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    MT3 metallothionein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820771, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MT3
    Official Full Name
    metallothionein 3
    Primary source
    TAIR:AT3G15353
    Locus tag
    AT3G15353
    See related
    Araport:AT3G15353
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMT3; metallothionein 3
    Summary
    metallothionein, binds to and detoxifies excess copper and other metals, limiting oxidative damage
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    Genomic context

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    See MT3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (5180642..5181586, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene cytochrome c oxidase 17 Neighboring gene ncRNA Neighboring gene ubiquitin-conjugating enzyme 25 Neighboring gene phosphopantothenoylcysteine decarboxylase subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and immunological identification of metallothioneins 1 and 2 from Arabidopsis thaliana. Murphy A, et al. Plant Physiol, 1997 Apr. PMID 9112777, Free PMC Article
    2. Examining the specific contributions of individual Arabidopsis metallothioneins to copper distribution and metal tolerance. Guo WJ, et al. Plant Physiol, 2008 Apr. PMID 18287486, Free PMC Article
    3. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112401.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular detoxification ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in intracellular copper ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular copper ion homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    metallothionein 3
    NP_001189899.1
    • metallothionein 3 (MT3); FUNCTIONS IN: copper ion binding; INVOLVED IN: cellular copper ion homeostasis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages.
    NP_566509.1
    • metallothionein 3 (MT3); Has 268 Blast hits to 268 proteins in 64 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 268; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5180642..5181586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202970.1 → NP_001189899.1  metallothionein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189899.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EL44, F4IYQ2

    2. NM_112401.2 → NP_566509.1  metallothionein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22433
      UniProtKB/TrEMBL
      A0A178VJJ5, A0A5S9XCI5, A0A7G2EL44
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22433.1

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