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    PUB8 plant U-box 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827885, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUB8
    Official Full Name
    plant U-box 8
    Primary source
    TAIR:AT4G21350
    Locus tag
    AT4G21350
    See related
    Araport:AT4G21350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    B80; plant U-box 8; T6K22.80; T6K22_80
    Summary
    Encodes a U-box/ARM repeat protein required fore self-incompatibility.
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    Genomic context

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    See PUB8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (11356143..11357267, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. U-box E3 ubiquitin ligase PUB8 attenuates abscisic acid responses during early seedling growth. Li Z, et al. Plant Physiol, 2023 Apr 3. PMID 36715300, Free PMC Article
    2. A cryptic modifier causing transient self-incompatibility in Arabidopsis thaliana. Liu P, et al. Curr Biol, 2007 Apr 17. PMID 17412590, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_118255.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in abscisic acid-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein ubiquitination NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plant U-box 8
    NP_193866.1
    • plant U-box 8 (PUB8); FUNCTIONS IN: ubiquitin-protein ligase activity, binding, zinc ion binding; INVOLVED IN: protein ubiquitination; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), U box domain (InterPro:IPR003613), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: plant U-box 13 (TAIR:AT3G46510.1); Has 3561 Blast hits to 3109 proteins in 223 species: Archae - 0; Bacteria - 18; Metazoa - 344; Fungi - 298; Plants - 2564; Viruses - 3; Other Eukaryotes - 334 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11356143..11357267 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118255.1 → NP_193866.1  plant U-box 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193866.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A3RCC8, A7Y5W2, O81902
      UniProtKB/TrEMBL
      A0A178UW78
      Conserved Domains (3) summary
      smart00504
      Location:8 → 72
      Ubox; Modified RING finger domain
      cd00020
      Location:173 → 284
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00043
      Location:179 → 204
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81902.1

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