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    GRF8 growth-regulating factor 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828515, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GRF8
    Official Full Name
    growth-regulating factor 8
    Primary source
    TAIR:AT4G24150
    Locus tag
    AT4G24150
    See related
    Araport:AT4G24150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGRF8; AtMIN10; growth-regulating factor 8; T19F6.140; T19F6_140
    Summary
    Growth regulating factor encoding transcription activator. One of the nine members of a GRF gene family, containing nuclear targeting domain. Involved in leaf development and expressed in shoot and flower.
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    Genomic context

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    See GRF8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (12535972..12539576)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene DUF538 family protein (Protein of unknown function, DUF538) Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ATP binding microtubule motor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis. Kim JH, et al. Plant J, 2003 Oct. PMID 12974814
    2. Molecular mechanism of microRNA396 mediating pistil development in Arabidopsis. Liang G, et al. Plant Physiol, 2014 Jan. PMID 24285851, Free PMC Article
    3. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001341644.1
    NM_001341645.1
    NM_118547.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within leaf development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast envelope HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth-regulating factor 8
    NP_194146.1
    • growth-regulating factor 8 (GRF8); FUNCTIONS IN: transcription activator activity; INVOLVED IN: leaf development; LOCATED IN: nucleus, chloroplast envelope; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine-Leucine-Glutamine, QLQ (InterPro:IPR014978), WRC (InterPro:IPR014977); BEST Arabidopsis thaliana protein match is: growth-regulating factor 7 (TAIR:AT5G53660.1); Has 485 Blast hits to 474 proteins in 17 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 485; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12535972..12539576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118547.2 → NP_194146.1  growth-regulating factor 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194146.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22976, Q9SU44
      UniProtKB/TrEMBL
      A0A5S9XVG1, A0A654FS86
      Conserved Domains (2) summary
      pfam08879
      Location:245 → 285
      WRC; WRC
      pfam08880
      Location:149 → 181
      QLQ; QLQ

    2. NM_001341644.1 → NP_001329478.1  growth-regulating factor 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7V6, A0A5S9XVG1, A0A654FS86

    3. NM_001341645.1 → NP_001329477.1  growth-regulating factor 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UU36, A0A1P8B7W1
      Conserved Domains (2) summary
      pfam08879
      Location:182 → 222
      WRC
      pfam08880
      Location:111 → 143
      QLQ
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SU44.1

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