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    AAC3 ADP/ATP carrier 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828955, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AAC3
    Official Full Name
    ADP/ATP carrier 3
    Primary source
    TAIR:AT4G28390
    Locus tag
    AT4G28390
    See related
    Araport:AT4G28390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ADP/ATP carrier 3; ATAAC3; F20O9.60; F20O9_60
    Summary
    Encodes a mitochondrial ADP/ATP carrier protein. Shown in heterologous systems to be located in the plasma membrane. Has comparable affinity for ADP and ATP (in E.coli).
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    Genomic context

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    See AAC3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14041288..14043347, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene non-specific lipid-transfer-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids. Haferkamp I, et al. Eur J Biochem, 2002 Jul. PMID 12084057
    2. The Arabidopsis class II sirtuin is a lysine deacetylase and interacts with mitochondrial energy metabolism. König AC, et al. Plant Physiol, 2014 Mar. PMID 24424322, Free PMC Article
    3. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609
    4. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001341915.1
    NM_118980.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP:ADP antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP:ADP antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial ADP transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial ATP transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within purine nucleotide transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast envelope HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    ADP/ATP carrier 3
    NP_194568.1
    • ADP/ATP carrier 3 (AAC3); FUNCTIONS IN: binding, ATP:ADP antiporter activity; INVOLVED IN: transport, mitochondrial transport, purine nucleotide transport; LOCATED IN: mitochondrion, mitochondrial inner membrane, membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial carrier protein (InterPro:IPR002067), Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: ADP/ATP carrier 2 (TAIR:AT5G13490.2); Has 20286 Blast hits to 12392 proteins in 480 species: Archae - 0; Bacteria - 0; Metazoa - 9416; Fungi - 5054; Plants - 3787; Viruses - 0; Other Eukaryotes - 2029 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14041288..14043347 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118980.4 → NP_194568.1  ADP/ATP carrier 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194568.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49447, Q8L9Y1
      UniProtKB/TrEMBL
      A0A178V026, A0A5S9XWM8
      Conserved Domains (1) summary
      PTZ00169
      Location:77 → 366
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

    2. NM_001341915.1 → NP_001328166.1  ADP/ATP carrier 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49447, Q8L9Y1
      UniProtKB/TrEMBL
      A0A178V026, A0A5S9XWM8
      Conserved Domains (1) summary
      PTZ00169
      Location:77 → 366
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49447.1

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