U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FIP37 FKBP12 interacting protein 37 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824584, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FIP37
    Official Full Name
    FKBP12 interacting protein 37
    Primary source
    TAIR:AT3G54170
    Locus tag
    AT3G54170
    See related
    Araport:AT3G54170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATFIP37; FKBP12 interacting protein 37
    Summary
    Encodes protein that binds FKBP12. This interaction is disrupted by FK506 but not by cyclosporin A.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FIP37 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (20056664..20059583)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene RNI-like superfamily protein Neighboring gene cyclin-dependent kinase B1;1 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. N(6)-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis. Shen L, et al. Dev Cell, 2016 Jul 25. PMID 27396363, Free PMC Article
    2. The blue light receptor CRY1 interacts with FIP37 to promote N(6) -methyladenosine RNA modification and photomorphogenesis in Arabidopsis. Yang J, et al. New Phytol, 2023 Feb. PMID 36305219
    3. MTA is an Arabidopsis messenger RNA adenosine methylase and interacts with a homolog of a sex-specific splicing factor. Zhong S, et al. Plant Cell, 2008 May. PMID 18505803, Free PMC Article
    4. An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506. Faure JD, et al. Plant J, 1998 Sep. PMID 9807817
    5. Identification of factors required for m(6) A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI. Růžička K, et al. New Phytol, 2017 Jul. PMID 28503769, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_115277.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meristem maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to blue light IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA N6-methyladenosine methyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    FKBP12 interacting protein 37
    NP_190985.1
    • FKBP12 interacting protein 37 (FIP37); Has 21268 Blast hits to 13212 proteins in 1142 species: Archae - 433; Bacteria - 2157; Metazoa - 10991; Fungi - 1638; Plants - 938; Viruses - 51; Other Eukaryotes - 5060 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20056664..20059583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115277.5 → NP_190985.1  FKBP12 interacting protein 37 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190985.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZSZ8
      UniProtKB/TrEMBL
      A0A178V9T4, A0A5S9XKN4
      Conserved Domains (1) summary
      pfam17098
      Location:127 → 280
      Wtap; WTAP/Mum2p family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZSZ8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools