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    SVR3 elongation factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831209, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SVR3
    Official Full Name
    elongation factor family protein
    Primary source
    TAIR:AT5G13650
    Locus tag
    AT5G13650
    See related
    Araport:AT5G13650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SUPPRESSOR OF VARIEGATION 3; T6I14.3
    Summary
    Encodes SVR3, a putative chloroplast TypA translation elongation GTPase. Loss of SVR3 suppresses variegation mediated by var2. SVR3 is essential for plants#Aeo ability to develop functional chloroplasts under chilling stress (8C), but not at normal temperature (22C).
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    Genomic context

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    See SVR3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Sequence:
    Chromosome: 5; NC_003076.8 (4397578..4402692)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene magnesium-chelatase subunit chlH, chloroplast, putative / Mg-protoporphyrin IX chelatase, putative (CHLH) Neighboring gene phospholipid:diacylglycerol acyltransferase Neighboring gene pseudo Neighboring gene N-lysine methyltransferase Neighboring gene nodulin MtN21 /EamA-like transporter family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 'happy on norflurazon' (hon) mutations implicate perturbance of plastid homeostasis with activating stress acclimatization and changing nuclear gene expression in norflurazon-treated seedlings. Saini G, et al. Plant J, 2011 Mar. PMID 21208309
    2. A var2 leaf variegation suppressor locus, SUPPRESSOR OF VARIEGATION3, encodes a putative chloroplast translation elongation factor that is important for chloroplast development in the cold. Liu X, et al. BMC Plant Biol, 2010 Dec 28. PMID 21187014, Free PMC Article
    3. Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm. Kim MH, et al. Cell Stress Chaperones, 2013 Jul. PMID 23334891, Free PMC Article
    4. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202
    5. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Findings reinforce the strong genetic link between VAR2 and chloroplast translation, and point to a critical role of SVR3, and possibly some aspects of chloroplast translation, in the response of plants to chilling stress.
      Title: A var2 leaf variegation suppressor locus, SUPPRESSOR OF VARIEGATION3, encodes a putative chloroplast translation elongation factor that is important for chloroplast development in the cold.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121368.4
    NM_180704.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast RNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to reactive oxygen species IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    elongation factor family protein
    NP_568289.3
    • elongation factor family protein; FUNCTIONS IN: GTP binding, translation elongation factor activity, GTPase activity; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation elongation factor EFG/EF2, C-terminal (InterPro:IPR000640), GTP-binding protein TypA (InterPro:IPR006298), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Elongation factor G/III/V (InterPro:IPR009022), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: elongation factor family protein (TAIR:AT2G31060.2); Has 76334 Blast hits to 67578 proteins in 6162 species: Archae - 1271; Bacteria - 47471; Metazoa - 3896; Fungi - 2458; Plants - 1891; Viruses - 1; Other Eukaryotes - 19346 (source: NCBI BLink).
    NP_851035.1
    • elongation factor family protein; FUNCTIONS IN: GTP binding, translation elongation factor activity, GTPase activity; LOCATED IN: chloroplast, chloroplast stroma; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation elongation factor EFG/EF2, C-terminal (InterPro:IPR000640), GTP-binding protein TypA (InterPro:IPR006298), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Elongation factor G/III/V (InterPro:IPR009022), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: elongation factor family protein (TAIR:AT2G31060.2); Has 77233 Blast hits to 68351 proteins in 6199 species: Archae - 1276; Bacteria - 48297; Metazoa - 3947; Fungi - 2455; Plants - 1903; Viruses - 1; Other Eukaryotes - 19354 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4397578..4402692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121368.4 → NP_568289.3  elongation factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568289.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UNX2, A0A7G2FEC8, F4K409
      Conserved Domains (1) summary
      TIGR01394
      Location:83 → 676
      TypA_BipA; GTP-binding protein TypA/BipA

    2. NM_180704.2 → NP_851035.1  elongation factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851035.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K410, Q93Y02, Q9FNA8
      UniProtKB/TrEMBL
      A0A178UMQ9, A0A7G2FCC7
      Conserved Domains (1) summary
      TIGR01394
      Location:82 → 675
      TypA_BipA; GTP-binding protein TypA/BipA
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4K410.1

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