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    MYB28 myb domain protein 28 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836263, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MYB28
    Official Full Name
    myb domain protein 28
    Primary source
    TAIR:AT5G61420
    Locus tag
    AT5G61420
    See related
    Araport:AT5G61420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtMYB28; HAG1; HIGH ALIPHATIC GLUCOSINOLATE 1; MFB13.22; MFB13_22; myb domain protein 28; PMG1; PRODUCTION OF METHIONINE-DERIVED GLUCOSINOLATE 1
    Summary
    Encodes a nuclear localized member of the MYB transcription factor family. Involved in positive regulation of aliphatic glucosinolate biosynthesis.Expression is induced by touch, wounding and glucose.
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    Genomic context

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    See MYB28 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (24689069..24691187, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene D-ribulose-5-phosphate-3-epimerase Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene NAC domain containing protein 100

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The R2R3-MYB transcription factor HAG1/MYB28 is a regulator of methionine-derived glucosinolate biosynthesis in Arabidopsis thaliana. Gigolashvili T, et al. Plant J, 2007 Jul. PMID 17521412
    2. Arabidopsis MYB28 and MYB29 transcription factors are involved in ammonium-mediated alterations of root-system architecture. Bejarano I, et al. Plant Signal Behav, 2021 Apr 3. PMID 33538226, Free PMC Article
    3. Glucose signalling positively regulates aliphatic glucosinolate biosynthesis. Miao H, et al. J Exp Bot, 2013 Feb. PMID 23329848, Free PMC Article
    4. Inhibition of SIZ1-mediated SUMOylation of HOOKLESS1 promotes light-induced apical hook opening in Arabidopsis. Xiong J, et al. Plant Cell, 2023 May 29. PMID 36890719, Free PMC Article
    5. Novel insights into the function of Arabidopsis R2R3-MYB transcription factors regulating aliphatic glucosinolate biosynthesis. Li Y, et al. Plant Cell Physiol, 2013 Aug. PMID 23792303

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Inhibition of SIZ1-mediated SUMOylation of HOOKLESS1 promotes light-induced apical hook opening in Arabidopsis.
      Title: Inhibition of SIZ1-mediated SUMOylation of HOOKLESS1 promotes light-induced apical hook opening in Arabidopsis.
    2. Arabidopsis MYB28 and MYB29 transcription factors are involved in ammonium-mediated alterations of root-system architecture.
      Title: Arabidopsis MYB28 and MYB29 transcription factors are involved in ammonium-mediated alterations of root-system architecture.
    3. MYB28 expression was induced by sulfur deficiency, while the expression levels of MYB29 and MYB76 were positively correlated with sulfur concentration.
      Title: Novel insights into the function of Arabidopsis R2R3-MYB transcription factors regulating aliphatic glucosinolate biosynthesis.
    4. MYB28 and MYB29 synergistically functioned in the glucose-induced biosynthesis of aliphatic glucosinolates, but MYB28 was predominant over MYB29.
      Title: Glucose signalling positively regulates aliphatic glucosinolate biosynthesis.
    5. Mutant plants deficient in camalexin, indole, or aliphatic glucosinolate biosynthesis were hypersusceptible to S. sclerotiorum, among them the myb28 mutant, which has a defect resulting in decreased production of long-chained aliphatic glucosinolates.
      Title: Role of camalexin, indole glucosinolates, and side chain modification of glucosinolate-derived isothiocyanates in defense of Arabidopsis against Sclerotinia sclerotiorum.
    6. MYB76 is not dependent on MYB28 and MYB29 for induction of aliphatic glucosinolates.
      Title: A complex interplay of three R2R3 MYB transcription factors determines the profile of aliphatic glucosinolates in Arabidopsis.
    7. Myb28 is a positive regulator for basal-level production of aliphatic glucosinolates.
      Title: Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis.
    8. We hypothesize that HAG1/MYB28 is a novel regulator of aliphatic glucosinolate biosynthesis that controls the response to biotic challenges
      Title: The R2R3-MYB transcription factor HAG1/MYB28 is a regulator of methionine-derived glucosinolate biosynthesis in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125535.4
    NM_180910.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to sulfur starvation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within induced systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to insect IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myb domain protein 28
    NP_200950.1
    • myb domain protein 28 (MYB28); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 29 (TAIR:AT5G07690.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851241.1
    • myb domain protein 28 (MYB28); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 76 (TAIR:AT5G07700.1); Has 5906 Blast hits to 5134 proteins in 359 species: Archae - 0; Bacteria - 112; Metazoa - 464; Fungi - 135; Plants - 4393; Viruses - 3; Other Eukaryotes - 799 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24689069..24691187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125535.4 → NP_200950.1  myb domain protein 28 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200950.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K3H4, Q9SPG2
      UniProtKB/TrEMBL
      A0A178UN88, A0A5S9YGQ9, A0A7G2FP11
      Conserved Domains (1) summary
      PLN03091
      Location:1 → 193
      PLN03091; hypothetical protein; Provisional

    2. NM_180910.2 → NP_851241.1  myb domain protein 28 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851241.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SPG2
      Conserved Domains (1) summary
      pfam00249
      Location:2 → 33
      Myb_DNA-binding; Myb-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SPG2.1

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