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    TCP8 TCP family transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842177, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TCP8
    Official Full Name
    TCP family transcription factor
    Primary source
    TAIR:AT1G58100
    Locus tag
    AT1G58100
    See related
    Araport:AT1G58100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTCP8; T15M6.11; TCP domain protein 8
    Summary
    Encodes TCP8, belongs to the TCP transcription factor family known to bind site II elements in promoter regions.
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    Genomic context

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    See TCP8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (21512332..21514189, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ATP phosphoribosyl transferase 1 Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The N-terminal region located upstream of the TCP domain is responsible for the antagonistic action of the Arabidopsis thaliana TCP8 and TCP23 transcription factors on flowering time. Camoirano A, et al. Plant Sci, 2023 Mar. PMID 36535527
    2. Overexpression of TCP8 delays Arabidopsis flowering through a FLOWERING LOCUS C-dependent pathway. Wang X, et al. BMC Plant Biol, 2019 Dec 3. PMID 31795938, Free PMC Article
    3. The intrinsically disordered C-terminal region of Arabidopsis thaliana TCP8 transcription factor acts both as a transactivation and self-assembly domain. Valsecchi I, et al. Mol Biosyst, 2013 Sep. PMID 23760157
    4. An Arabidopsis dual-localized pentatricopeptide repeat protein interacts with nuclear proteins involved in gene expression regulation. Hammani K, et al. Plant Cell, 2011 Feb. PMID 21297037, Free PMC Article
    5. Analysis of the role of Arabidopsis class I TCP genes AtTCP7, AtTCP8, AtTCP22, and AtTCP23 in leaf development. Aguilar-Martínez JA, et al. Front Plant Sci, 2013. PMID 24137171, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The N-terminal region located upstream of the TCP domain is responsible for the antagonistic action of the Arabidopsis thaliana TCP8 and TCP23 transcription factors on flowering time.
      Title: The N-terminal region located upstream of the TCP domain is responsible for the antagonistic action of the Arabidopsis thaliana TCP8 and TCP23 transcription factors on flowering time.
    2. Overexpression of TCP8 significantly delayed flowering under both long-day and short-day conditions and dominant repression by TCP8 led to various growth defects. The upregulation of TCP8 led to more accumulated mRNA level of FLOWERING LOCUS C (FLC), a central floral repressor of Arabidopsis.
      Title: Overexpression of TCP8 delays Arabidopsis flowering through a FLOWERING LOCUS C-dependent pathway.
    3. TCP proteins are involved in the orchestrated regulation of ICS1 expression, with TCP8 and TCP9 being verified as major representatives.
      Title: TCP transcription factors are critical for the coordinated regulation of isochorismate synthase 1 expression in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084270.1
    NM_104592.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TCP family transcription factor
    NP_001077739.1
    • TCP family transcription factor; FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP family transcription factor (TAIR:AT1G35560.1); Has 396 Blast hits to 390 proteins in 36 species: Archae - 0; Bacteria - 3; Metazoa - 45; Fungi - 2; Plants - 334; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).
    NP_176107.1
    • TCP family transcription factor; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP family transcription factor (TAIR:AT1G35560.1); Has 469 Blast hits to 463 proteins in 47 species: Archae - 0; Bacteria - 0; Metazoa - 51; Fungi - 2; Plants - 404; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21512332..21514189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104592.5 → NP_176107.1  TCP family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176107.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQM9, Q9C518
      UniProtKB/TrEMBL
      A0A178WFL5
      Conserved Domains (1) summary
      pfam03634
      Location:59 → 144
      TCP; TCP family transcription factor

    2. NM_001084270.1 → NP_001077739.1  TCP family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077739.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WFL5
      Conserved Domains (1) summary
      cl23822
      Location:59 → 92
      TCP; TCP family transcription factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C518.1

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