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    ATDAD1 Defender against death (DAD family) protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840113, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATDAD1
    Official Full Name
    Defender against death (DAD family) protein
    Primary source
    TAIR:AT1G32210
    Locus tag
    AT1G32210
    See related
    Araport:AT1G32210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DEFENDER AGAINST APOPTOTIC DEATH 1; F3C3.14; F3C3_14
    Summary
    Encodes protein involved in suppression of apoptosis. Complements a mammalian apoptosis suppressor mutation.
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    Genomic context

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    See ATDAD1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (11605606..11607866, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phospholipid/glycerol acyltransferase family protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein Neighboring gene WWE protein-protein interaction domain protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis thaliana cDNA complementing a hamster apoptosis suppressor mutant. Gallois P, et al. Plant J, 1997 Jun. PMID 9225471
    2. OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels. Beaugelin I, et al. Plant Physiol, 2019 Jul. PMID 31123095, Free PMC Article
    3. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels.
      Title: OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102954.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of programmed cell death IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    part_of oligosaccharyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Defender against death (DAD family) protein
    NP_174500.1
    • DEFENDER AGAINST APOPTOTIC DEATH 1 (ATDAD1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: anti-apoptosis; LOCATED IN: endoplasmic reticulum, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Defender against death DAD protein (InterPro:IPR003038); BEST Arabidopsis thaliana protein match is: Defender against death (DAD family) protein (TAIR:AT2G35520.1); Has 458 Blast hits to 458 proteins in 196 species: Archae - 0; Bacteria - 0; Metazoa - 197; Fungi - 115; Plants - 102; Viruses - 0; Other Eukaryotes - 44 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11605606..11607866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332997.1 → NP_001320444.1  Defender against death (DAD family) protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMW1

    2. NM_102954.4 → NP_174500.1  Defender against death (DAD family) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174500.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39080, Q53WQ9
      UniProtKB/TrEMBL
      A0A178WL80, A0A5S9WKT6
      Conserved Domains (1) summary
      pfam02109
      Location:10 → 115
      DAD; DAD family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39080.2

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