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    TFIIB transcription factor IIB [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818761, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TFIIB
    Official Full Name
    transcription factor IIB
    Primary source
    TAIR:AT2G41630
    Locus tag
    AT2G41630
    See related
    Araport:AT2G41630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTFIIB1; T32G6.15; T32G6_15; TFIIB1; transcription factor IIB; transcription factor IIB 1; TRANSCRIPTION FACTOR TFIIB
    Summary
    Encodes a transcription factor, TFIIB1, that plays important roles in pollen tube growth, guidance, and reception as well as endosperm development and is partially functionally different from AtTFIIB2 and AtTFIIB3/AtpBRP2.
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    Genomic context

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    See TFIIB in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (17355299..17357622, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nucleoporin interacting component (Nup93/Nic96-like) family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Glycosyltransferase family 61 protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis general transcription factor TFIIB1 (AtTFIIB1) is required for pollen tube growth and endosperm development. Zhou JJ, et al. J Exp Bot, 2013 May. PMID 23547107, Free PMC Article
    2. Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks. Reiland S, et al. Plant Physiol, 2009 Jun. PMID 19376835, Free PMC Article
    3. Pollen-expressed transcription factor 2 encodes a novel plant-specific TFIIB-related protein that is required for pollen germination and embryogenesis in Arabidopsis. Niu QK, et al. Mol Plant, 2013 Jul. PMID 23713077
    4. Arabidopsis thaliana GYRB3 does not encode a DNA gyrase subunit. Evans-Roberts KM, et al. PLoS One, 2010 Mar 26. PMID 20360860, Free PMC Article
    5. Plant homeodomain-leucine zipper I transcription factors exhibit different functional AHA motifs that selectively interact with TBP or/and TFIIB. Capella M, et al. Plant Cell Rep, 2014 Jun. PMID 24531799

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129726.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables TBP-class protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within endosperm development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor IIB
    NP_181694.1
    • transcription factor IIB (TFIIB); FUNCTIONS IN: RNA polymerase II transcription factor activity, transcription regulator activity, zinc ion binding, translation initiation factor activity; INVOLVED IN: translational initiation, regulation of transcription, DNA-dependent, transcription initiation, regulation of transcription; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor TFIIB related (InterPro:IPR000812), Cyclin-like (InterPro:IPR011028), Transcription factor TFIIB, cyclin-related (InterPro:IPR013150), Zinc finger, TFIIB-type (InterPro:IPR013137), Cyclin-related (InterPro:IPR013763), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin-like family protein (TAIR:AT3G10330.1); Has 1967 Blast hits to 1965 proteins in 361 species: Archae - 538; Bacteria - 1; Metazoa - 305; Fungi - 294; Plants - 195; Viruses - 14; Other Eukaryotes - 620 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17355299..17357622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129726.4 → NP_181694.1  transcription factor IIB [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181694.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48512, Q53YU0
      UniProtKB/TrEMBL
      A0A178VYM4, A0A5S9X640, A0A7G2EFE9
      Conserved Domains (1) summary
      COG1405
      Location:6 → 298
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48512.1

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