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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823589, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT3G44630
    Locus tag
    AT3G44630
    See related
    Araport:AT3G44630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (16195848..16201225)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene protein-tyrosine phosphatase Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NDR1, a pathogen-induced component required for Arabidopsis disease resistance. Century KS, et al. Science, 1997 Dec 12. PMID 9395402
    2. The TOPLESS interactome: a framework for gene repression in Arabidopsis. Causier B, et al. Plant Physiol, 2012 Jan. PMID 22065421, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001339160.1
    NM_114331.3
    NM_180323.4
    NM_180324.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_190049.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: N-terminal protein myristoylation, defense response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G44480.1); Has 41227 Blast hits to 23573 proteins in 843 species: Archae - 26; Bacteria - 2454; Metazoa - 3797; Fungi - 287; Plants - 32967; Viruses - 4; Other Eukaryotes - 1692 (source: NCBI BLink).
    NP_850654.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G44480.1); Has 41227 Blast hits to 23573 proteins in 843 species: Archae - 26; Bacteria - 2454; Metazoa - 3797; Fungi - 287; Plants - 32967; Viruses - 4; Other Eukaryotes - 1692 (source: NCBI BLink).
    NP_850655.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G44480.1); Has 41236 Blast hits to 23630 proteins in 841 species: Archae - 26; Bacteria - 2523; Metazoa - 3794; Fungi - 289; Plants - 32905; Viruses - 4; Other Eukaryotes - 1695 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16195848..16201225
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114331.3 → NP_190049.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190049.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7U882, Q9M1P1
      Conserved Domains (6) summary
      cd00009
      Location:283 → 411
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      cd09293
      Location:809 → 974
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:89 → 1107
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:741 → 764
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:94 → 259
      TIR; TIR domain
      pfam07725
      Location:717 → 736
      LRR_3; Leucine Rich Repeat

    2. NM_001339160.1 → NP_001327594.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7U882, Q9M1P1

    3. NM_180323.4 → NP_850654.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850654.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7U882, Q9M1P1
      Conserved Domains (6) summary
      cd00009
      Location:283 → 411
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      cd09293
      Location:809 → 974
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:89 → 1107
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:741 → 764
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:94 → 259
      TIR; TIR domain
      pfam07725
      Location:717 → 736
      LRR_3; Leucine Rich Repeat

    4. NM_180324.2 → NP_850655.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850655.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7U882, F4J359
      Conserved Domains (6) summary
      cd00009
      Location:283 → 411
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      cd09293
      Location:809 → 974
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:89 → 1107
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:741 → 764
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:94 → 259
      TIR; TIR domain
      pfam07725
      Location:717 → 736
      LRR_3; Leucine Rich Repeat
    Nucleotide Protein
    Heading Accession and Version

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