GSTT1 glutathione S-transferase THETA 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GSTT1
Official Full Name: glutathione S-transferase THETA 1
Primary source: TAIR:AT5G41210
Locus tag: AT5G41210
See related: Araport:AT5G41210
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATGSTT1; glutathione S-transferase TAU 12; glutathione S-transferase THETA 1; GST10; GSTU12; MEE6.28; MEE6_28
Summary: Encodes glutathione transferase belonging to the theta class of GSTs. Naming convention according to Wagner et al. (2002).
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Genomic context

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See GSTT1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 7

Sequence:: Chromosome: 5; NC_003076.8 (16492275..16494059, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_123486.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within toxin catabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	NAS Non-traceable Author Statement more info	PubMed
located_in peroxisome	HDA more info	PubMed
located_in plastid	HDA more info	PubMed

General protein information

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Preferred Names: glutathione S-transferase THETA 1

NP_198937.1

glutathione S-transferase THETA 1 (GSTT1); FUNCTIONS IN: glutathione transferase activity; INVOLVED IN: toxin catabolic process; LOCATED IN: peroxisome, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Glutathione S-transferase, N-terminal (InterPro:IPR004045), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: glutathione S-transferase THETA 3 (TAIR:AT5G41220.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

16492275..16494059 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_123486.4 → NP_198937.1 glutathione S-transferase THETA 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_198937.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9ZRT5

UniProtKB/TrEMBL

A0A178UCY2, A0A5S9Y9U2, A0A654G6X7

Conserved Domains (2) summary

cd03183
Location:93 → 223

GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases

cd03050
Location:4 → 79

GST_N_Theta; GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with ...