GFA2 gametophytic factor 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: GFA2
Official Full Name: gametophytic factor 2
Primary source: TAIR:AT5G48030
Locus tag: AT5G48030
See related: Araport:AT5G48030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: gametophytic factor 2; MDN11.11; MDN11_11
Summary: encodes a mitochondrially targeted DNAJ protein involved in female gametophyte development.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_124177.4

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables heat shock protein binding	IEA Inferred from Electronic Annotation more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chaperone cofactor-dependent protein refolding	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within embryo sac cellularization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryo sac development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within nuclear membrane fusion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within polar nucleus fusion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to heat	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within synergid death	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

NP_568690.1

gametophytic factor 2 (GFA2); FUNCTIONS IN: unfolded protein binding, heat shock protein binding; INVOLVED IN: in 7 processes; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Molecular chaperone, heat shock protein, Hsp40, DnaJ (InterPro:IPR015609), HSP40/DnaJ peptide-binding (InterPro:IPR008971), Chaperone DnaJ, C-terminal (InterPro:IPR002939), Heat shock protein DnaJ, N-terminal (InterPro:IPR001623), Heat shock protein DnaJ, conserved site (InterPro:IPR018253), Heat shock protein DnaJ, cysteine-rich domain (InterPro:IPR001305), Heat shock protein DnaJ (InterPro:IPR003095); BEST Arabidopsis thaliana protein match is: DNAJ heat shock family protein (TAIR:AT1G28210.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

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