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    RAB1C RAB GTPase homolog 1C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827468, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB1C
    Official Full Name
    RAB GTPase homolog 1C
    Primary source
    TAIR:AT4G17530
    Locus tag
    AT4G17530
    See related
    Araport:AT4G17530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRAB1C; ATRABD2C; DL4800C; FCAALL.87; RAB GTPase homolog 1C
    Summary
    AtRabD2c encodes a Rab GTPase, which plays important roles in pollen development, germination and tube elongation.
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    Genomic context

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    See RAB1C in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (9773548..9775676, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ubiquitin C-terminal hydrolase 3 Neighboring gene miscRNA Neighboring gene Hyaluronan / mRNA binding family Neighboring gene dynamin Neighboring gene Major facilitator superfamily protein Neighboring gene Ribosomal protein L19 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtRabD2b and AtRabD2c have overlapping functions in pollen development and pollen tube growth. Peng J, et al. BMC Plant Biol, 2011 Jan 26. PMID 21269510, Free PMC Article
    2. Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway. Pinheiro H, et al. J Cell Sci, 2009 Oct 15. PMID 19789181, Free PMC Article
    3. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    4. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Findings support a partially redundant role for AtRabD2b and AtRabD2c in vesicle trafficking during pollen tube growth that cannot be fulfilled by the remaining AtRabD family members.[AtRabD2c]
      Title: AtRabD2b and AtRabD2c have overlapping functions in pollen development and pollen tube growth.
    2. The Rab-D1 and Rab-D2 subclasses have overlapping functions in the early secretory pathway. [Rab-D2c]
      Title: Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_117859.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog 1C
    NP_193486.1
    • RAB GTPase homolog 1C (RAB1C); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog 1A (TAIR:AT5G47200.1); Has 29496 Blast hits to 29428 proteins in 784 species: Archae - 23; Bacteria - 169; Metazoa - 15486; Fungi - 4134; Plants - 3462; Viruses - 20; Other Eukaryotes - 6202 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9773548..9775676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117859.4 → NP_193486.1  RAB GTPase homolog 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193486.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23594, Q8W4S8, Q9SEH3
      UniProtKB/TrEMBL
      A0A178USY3, A0A5S9XTL6, A0A7G2F3C7
      Conserved Domains (1) summary
      cd01869
      Location:7 → 172
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SEH3.1

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