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    ALPHA-VPE alpha-vacuolar processing enzyme [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817135, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALPHA-VPE
    Official Full Name
    alpha-vacuolar processing enzyme
    Primary source
    TAIR:AT2G25940
    Locus tag
    AT2G25940
    See related
    Araport:AT2G25940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha-vacuolar processing enzyme; ALPHAVPE; F17H15.4
    Summary
    Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteinases that is expressed in vegetative organs and is upregulated in association with various types of cell death and under stressed conditions.
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    Genomic context

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    See ALPHA-VPE in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (11063301..11066184, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pollen-specific LRR extensin-like protein Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene PITH domain protein (DUF1000) Neighboring gene uncharacterized protein Neighboring gene KH domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Homologues of a vacuolar processing enzyme that are expressed in different organs in Arabidopsis thaliana. Kinoshita T, et al. Plant Mol Biol, 1995 Oct. PMID 7579169
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_128154.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vacuolar protein processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in protein storage vacuole ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in vacuole ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-vacuolar processing enzyme
    NP_180165.1
    • alpha-vacuolar processing enzyme (ALPHA-VPE); FUNCTIONS IN: cysteine-type endopeptidase activity; INVOLVED IN: proteolysis, vacuolar protein processing; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C13, legumain (InterPro:IPR001096); BEST Arabidopsis thaliana protein match is: gamma vacuolar processing enzyme (TAIR:AT4G32940.1); Has 793 Blast hits to 791 proteins in 239 species: Archae - 4; Bacteria - 12; Metazoa - 278; Fungi - 115; Plants - 259; Viruses - 0; Other Eukaryotes - 125 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11063301..11066184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128154.5 → NP_180165.1  alpha-vacuolar processing enzyme [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82806, P49047, Q7GAI8
      UniProtKB/TrEMBL
      A0A178VQP4
      Conserved Domains (1) summary
      pfam01650
      Location:44 → 314
      Peptidase_C13; Peptidase C13 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P49047.2

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